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Found 455 clinical trials
Phase I Clinical Trial to Determine the Safety of Clonidine in Infants With HIE During Therapeutic Hypothermia.

required. Escalating doses of opioids and benzodiazepines causes respiratory depression and can either cause the need for or prolong mechanical ventilation.Agonists to the central a2 - adrenergic

  • 14 views
  • 08 Nov, 2020
  • 1 location
Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication

The purpose of this study is to evaluate the feasibility of use of a wearable communication device for critically ill patients who are admitted to the intensive care unit (ICU) and mechanically ventilated. The study will assess the safety, tolerability, and ease of use of the EyeControl device, and examine …

  • 4 views
  • 03 May, 2022
  • 1 location
Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia

the drug will help patients recover more quickly and slow down the progression of acute respiratory failure.

  • 0 views
  • 15 Dec, 2021
  • 1 location
Pro-thrombotic Status in Patients With SARS-Cov-2 Infection (ATTAC-Co)

The present study is ideated to prospectively investigate in patients with severe acute respiratory syndrome (SARS) due to Coronavirus 19 (SARS-Cov-2) infection and moderate-severe respiratory

respiratory failure
SARS
pao2
coronavirus infection
mechanical ventilation
  • 0 views
  • 04 Mar, 2022
  • 1 location
Opioid Free Total Intravenous Anesthesia Within an Enhanced Recovery After Surgery Pathway for Bariatric Surgery: A Randomized Controlled Clinical Trial

The morbidly obese bariatric surgery population is susceptible to opioid-induced complications such as respiratory depression and postoperative nausea and vomiting. This population may in

  • 67 views
  • 21 Oct, 2022
  • 1 location
Outpatient Liquid Aspirin (OLA) (OLA COVID)

coagulopathy (CAC) . The potential impact is to reduce COVID-19 related hospitalization within 30 days of diagnosis due to (1) pulmonary events including respiratory failure; (2) cardiac events including

  • 0 views
  • 26 Mar, 2022
  • 1 location
Ultrasound Guided Pericapsular Nerve Group Block Versus Quadratus Lumborum Block

mobilization and hospital discharge. Traditional use of opioids is associated with many adverse effects such as sedation, dizziness, nausea, vomiting, constipation and respiratory depression. Previous

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Physiological Study to Assess Awake Prone Positioning and Respiratory Support in Healthy Volunteers

Awake prone positioning (APP) has been proven to reduce the intubation rate for patients with COVID-19-induced hypoxemic respiratory failure. Our recent meta-analysis found APP was only

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Effect of Intraoperative Lidocaine Infusion on Inducing Intestinal Motility and Surgery-induced Release of Pro-inflammatory Cytokines After Abdominal Surgery. A Prospective, Comparative, Randomized Double Blind Controlled Clinical Study

the perioperative setting were conducted in the late 1950s where IV Lidocaine was demonstrated to have a postoperative analgesic effect without posing the risk of respiratory depression, reducing the

  • 0 views
  • 11 Oct, 2022
  • 1 location
Nasal High-Flow in COPD (High-TeC)

, and the University of Twente, collaborating. Study population: One hundred thirty-six patients with known COPD GOLD stage II to IV and hypoxemic respiratory failure hospitalised with a COPD

respiratory symptoms
pulmonary disease
pao2
respiratory failure
obstructive lung disease
  • 0 views
  • 04 Oct, 2022
  • 3 locations