Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 447 clinical trials
A Multicenter Study of the Efficacy and Safety of Esketamine for Analgesia During Cesarean Section

This study proposed applying intravenous Esketamine to cesarean section in parturient, detecting the plasma concentration of Esketamine in maternal blood, neonatal umbilical venous blood and umbilical arterial blood when the baby is delivered ketamine blood drug concentration, observing vital signs, adverse visual analog pain score (VAS), and sedation score (Ramsay) …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings. (SPEED-UP)

Hypothesis In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who receive preventive therapy with high flow nasal cannula (HFNC), the use of SBT with "HIGH minimal ventilator …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Anticoagulation-free VV ECMO for Acute Respiratory Failure (A-FREE ECMO)

Currently international experts recommend therapeutic anticoagulation for veno-venous extracorporeal membrane oxygenation (VV-ECMO). Reports and case series suggest that the absence of therapeutic anticoagulation is safe for VV-ECMO. No randomized control trials have assessed this. The aim of this pilot study is to assess safety and feasibility of an "anticoagulation-free strategy" …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis (GRAIL^3)

This is a phase 3 study designed to evaluate whether the administration of ganciclovir increases ventilator-free days in immunocompetent patients with sepsis associated acute respiratory failure

  • 0 views
  • 04 Oct, 2022
  • 19 locations
  • 0 views
  • 17 May, 2022
  • 3 locations
Comparison of Non-invasive Methods of Lung Ventilation in Patients With Respiratory Failure in the Postoperative Period After Cardiac Surgery

Comparison of the effectiveness of three methods of non-invasive ventilation in patients with mild and moderate respiratory failure in the early postoperative period after cardiac surgery

Accepts healthy volunteers
non-invasive ventilation
pneumonia
assisted ventilation
pao2
  • 0 views
  • 17 Oct, 2022
  • 1 location
High Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypoxic Respiratory Failure Following Blunt Chest Trauma

to compare high flow nasal cannula against noninvasive ventilation in patients with non-sever blunt chest trauma in improvement of oxygenation, need for intubation and mechanical ventilation within 28 days

  • 0 views
  • 07 Oct, 2022
  • 1 location
Gas Exchange Derangement Physiopathology in Critically Ill Patients With COVID-19

The study was designed to understand the pathophysiology of gas exchange derangement in critically ill patients with COVID-19. Specifically we will evaluate the effect of 3 different levels of positive end-expiratory pressure (PEEP) and two different levels of inspiratory oxygen fraction (FiO2) on gas exchange by analyzing shunt and dead …

acute respiratory distress syndrome
positive end expiratory pressure
respiratory distress
mechanical ventilation
assisted ventilation
  • 0 views
  • 01 Dec, 2021
  • 1 location
Safety and Efficacy of Argatroban Applicated in Anticoagulation of V-V ECMO

Unfractionated heparin is most common in the anticoagulation management of V-V ECMO. However, many side effects of unfractionated heparin, such as HIT, antithrombin deficiency, etc seriously affects the prognosis of patients. Argatroban is kind of direct thrombin inhibitors, which could be used used as an alternative anticoagulant of unfractionated heparin …

  • 1 views
  • 16 Jul, 2021
  • 1 location
Cuff Pressure Control and Evacuation of Subglottic Secretions To Prevent Pneumonia

Multicenter, cluster randomized, controlled, open-label trial to assess if AnapnoGuard System can minimize tracheal microaspiration and the risk of ventilator-associated pneumonia when compared to standard treatment

intubation
pneumonia
assisted ventilation
mechanical ventilation
carbon dioxide
  • 0 views
  • 27 Jun, 2022
  • 1 location