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Found 3484 clinical trials
AMPLE-3: IPC Plus Talc vs VATS in Management of Malignant Pleural Effusion (AMPLE-3)

The purpose of this study is to determine if an indwelling catheter is more effective than surgical pleurodosis in treating malignant pleural effusion. Who is it for? You may be eligible for this study if you are an adult who is suffering from symptomatic proven pleural malignancy or an otherwise …

chest x-ray
pleural fluid analysis
indwelling catheter
malignant pleural effusion
pleurodesis
  • 1 views
  • 02 Mar, 2022
  • 1 location
Inhaled NO for the Treatment of Viral Pneumonia in Adults

The purpose of this multi center, open label, randomized, study is to obtain information on the safety and efficacy of 150 ppm Nitric Oxide given in addition to the standard of care of patients with viral pneumonia

nitric oxide
nasal swab
  • 0 views
  • 23 Mar, 2022
  • 3 locations
Effect of Dupilumab on Aspirin Intolerance

To test the efficacy of dupilumab in patients with AERD regarding the intolerance to salicylic acid after 6 months. This will be evaluated by oral drug provocation testing with low dose salicylic acid after 6 months of dupilumab treatment. Hypothesis After 6 months of therapy, patients will tolerate aspirin dose …

Accepts healthy volunteers
  • 0 views
  • 18 Apr, 2022
  • 1 location
Daily Vitamin D for Sickle-cell Respiratory Complications (ViDAS-2)

This study aims to answer the question whether daily oral vitamin D supplementation can reduce the risk of respiratory or lung complications in children and adolescents with sickle cell disease. Respiratory problems are the leading causes of sickness and of death in sickle cell disease. The investigators hypothesize that daily …

hb s
vitamins
beta-thalassemia
sickle cell disease
haemoglobin
  • 1 views
  • 15 Jul, 2022
  • 1 location
Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea

Drug-induced sleep endoscopy (DISE) is the most used technique for identifying the obstruction site associated with obstructive sleep apnea (OSA). This is due to the fact that it allows many patients to be examined in a daytime setting. This procedure uses sedative drugs to mimic natural sleep. However, associations with …

collapse
polysomnography
sedative
apnea
body mass index
  • 0 views
  • 05 Aug, 2021
  • 1 location
The Effectiveness Pulmonary Telerehabilitation and Cognitive Telerehabilitation in COPD Patients

The aim of our study is to compare the effectiveness of the supervized pulmonary telerehabilitation program and the cognitive telerehabilitation method, which includes pulmonary telerehabilitation methods, in patients with severe stage COPD who have difficulty exercising heavily. The effects of pulmonary and cognitive rehabilitation on dyspnea, muscle strength, functional capacity, …

pulmonary rehabilitation
dyspnea
COPD
  • 0 views
  • 22 Mar, 2022
  • 1 location
Real-time Effort Driven VENTilator Management (REDvent)

This study is a Phase II controlled clinical trial that will obtain comprehensive, serial assessments of respiratory muscle strength and architecture to understand the evolution of ventilator-induced respiratory muscle weakness in critically ill children, and test whether a novel computer-based approach (Real-time Effort Driven ventilator management (REDvent)) can preserve respiratory …

  • 0 views
  • 31 Jan, 2022
  • 1 location
Photodynamic Therapy for COVID-19 Prevention

This is a single-center open-label study to evaluate antimicrobial photodynamic therapy (aPDT) for upper airway decolonization in patients presenting with SARS-CoV-2 positive antigen test with mild or no symptoms of COVID-19.

  • 0 views
  • 22 Mar, 2022
  • 1 location
Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients With CRS

This is a proposed randomized prospective study to evaluate both the anti-inflammatory and analgesic effects of a COX-2 inhibitor, celecoxib, in patients with aspirin-exacerbated respiratory

  • 0 views
  • 21 Apr, 2022
  • 1 location
SOLIDARITY Finland Plus Long-COVID

The SOLIDARITY PLUS Finland Long-COVID trial aims to assess the long-term effects of imatinib and infliximab, used during acute hospitalization due to COVID-19-infection, on long-COVID symptoms and quality of life (QoL) using questionnaires at six months, one and two years post-discharge. The primary research questions are whether imatinib or infliximab …

  • 0 views
  • 17 May, 2022
  • 1 location