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Found 589 clinical trials
Featured trial
Longitudinal Observational Study of Severe Asthma

Background: Asthma is a lung condition that causes difficulty breathing and decreased lung function. Some people with asthma have more severe disease symptoms. They

allergic asthma
asthmatic
asthma
  • 22 views
  • 22 Dec, 2020
  • 1 location
None
High Flow Nasal Cannula With Noninvasive Ventilation

This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
ROX Index for the Timing of Intubation in Nasal High Flow

Late or delayed intubation in patients with acute hypoxemic respiratory failure (AHRF) treated with nasal high flow (NHF) is associated with increased patient mortality. The ROX index has been

  • 1 views
  • 03 Feb, 2021
  • 9 locations
None
ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19

This study looks at the safety and effectiveness of different drugs in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure

  • 42 views
  • 18 Nov, 2021
  • 55 locations
None
Continuous Wireless Monitoring of Vital Signs and Automated Alerts of Patient Deterioration in Patients Admitted With COVID-19 Infection

to 24 hours before a life-threatening event such as respiratory failure leading to ICU admission, or unanticipated cardiac arrest. Such adverse trends in clinical observations can be missed

  • 0 views
  • 28 Jan, 2021
  • 1 location
None
Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 ACUTE

This is a randomized, open label, adaptive platform trial to compare the effectiveness of antithrombotic and additional strategies for prevention of adverse outcomes in COVID-19 positive inpatients

  • 0 views
  • 05 Nov, 2021
  • 100 locations
None
Phase IIb Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) (Ad5-nCoV) in Adults 18 Years of Age and Older.

A randomized, double-blind, placebo -controlled, phase IIb clinical trial to evaluate the efficacy, safety and immunogenicity of one or two doses of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) in adults 18 years of age and older, living with HIV, on stable treatment, and virologically suppressed for at least …

  • 0 views
  • 01 Oct, 2021
  • 4 locations
None
Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy

This prospective, randomized, double blinded study is designed to compare the bleeding rates of ketorolac vs. placebo when used for post tonsillectomy pain control in pediatric patients ages 2-18.

  • 0 views
  • 02 Sep, 2021
  • 1 location
None
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings.

Hypothesis In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who receive preventive therapy with high flow nasal cannula (HFNC), the use of SBT with "HIGH minimal ventilator …

  • 0 views
  • 03 May, 2021
  • 1 location
None
Prone Position for Non-intubated Patients With Acute Respiratory Failure

The study will test the hypothesis that the prone position can be used to reduce the need for intubation and mechanical ventilation in patients with acute respiratory failure.

FIO2
acute respiratory failure
pao2
mechanical ventilation
intubation
  • 65 views
  • 07 Nov, 2020
  • 1 location