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Found 67 clinical trials
LYT-100 in Post-acute COVID-19 Respiratory Disease

This study is a randomized, double-blind, parallel arm study to evaluate the safety and efficacy of LYT-100 compared to placebo in adults with post-acute COVID-19 respiratory complications

  • 10 May, 2021
  • 17 locations
Driving Pressure During General Anesthesia for Open Abdominal Surgery

The purpose of this international multicenter, patient and outcome-assessor blinded randomized controlled trial is to determine whether the application of an individualized high PEEP strategy, aiming at avoiding an increase in the driving pressure during intraoperative ventilation, protects against the development of postoperative pulmonary complications.

  • 29 Jan, 2021
  • 22 locations
LUS and Consequences of High FiO2 in Children

investigate the correlation between lung consolidation score and patient clinical variables including pulmonary mechanics, Sao2%, ABG, and perioperative respiratory complications.

  • 28 Jan, 2021
  • 2 locations
Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19

Low radiation doses produce anti-inflammatory effects, which may be useful in the treatment of respiratory complications of COVID-19. This type of treatment is non-invasive and therefore, a

  • 25 Jan, 2021
  • 3 locations
Move For Surgery - A Novel Preconditioning Program

as 50% of patients will suffer respiratory complications after surgery, keeping them in the hospital for extended periods of time. These long hospitalizations have a dramatic negative effect on the

  • 27 Jan, 2021
  • 1 location
A Study of Inhaled Ampion in Adults With Respiratory Distress Due to COVID-19

This is phase II study to evaluate the safety and efficacy of inhaled Ampion in adults with respiratory distress due to COVID-19

  • 13 May, 2021
  • 1 location
A Pilot Study of Bupivacaine Infusion in Abdominal Surgery

The incisions used in abdominal surgery can be quite painful, requiring strong pain medications. A new pain pump that trickles small amounts of local freezing into the incision has been developed that helps numb the area so that the patient does not feel the pain for two to five days …

abdominal surgery
  • 07 Nov, 2020
  • 1 location
Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery

Postoperative ileus, defined as the transient postoperative functional inhibition of propulsive bowel activity, commonly occurs in patients after cardiac surgery and contributes to postoperative morbidity. Naloxegol is a peripheral opioid receptor antagonist. Recent studies showed that naloxegol is effective in the treatment of chronic opioid-induced constipation but there is no …

  • 26 Jan, 2021
  • 1 location
Preoperative Self-managed Respiratory Therapy for Reduction of Postoperative Pulmonary Complications

Postoperative pulmonary complications (PPCs) are a source of much morbidity and mortality. Rates of PPCs exceed 30% in patients with multiple risk factors. Several studies have demonstrated reduced PPCs in patients who underwent preoperative inspiratory muscle training. These studies largely focused on cardiothoracic surgery and required the use of respiratory …

  • 23 Jan, 2021
  • 1 location
Medicoeconomic Evaluation of Two Surgical Techniques for Lobectomy in the Lung Cancer

postoperative respiratory complications including atelectasis, pneumonia and Acute Respiratory Distress Syndrome (ARDS) is reduced. These respiratory complications are responsible for prolonged stays in

lung cancer
lung carcinoma
  • 23 Jan, 2021
  • 20 locations