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Found 29 clinical trials
Featured trial
Artisan

Artisan

  • 205 views
  • 08 Nov, 2020
  • 1 location
Neuroinflammation in Hypertension Study

To demonstrate that in patients with resistant hypertension oral treatment with minocycline via inhibition of central immune cell activation and inflammation results in reduced central

  • 1 views
  • 05 Oct, 2021
  • 1 location
MANP in African Americans With Hypertension (MANP-2)

Evaluate the cardiovascular properties of MANP in AA with Hypertension

Accepts healthy volunteers
  • 0 views
  • 09 Mar, 2022
  • 1 location
Randomized Study of Extended Treatment With Firibastat in Treatment-Resistant Hypertension (REFRESH)

This is a double-blind, placebo-controlled and open-label, multicenter efficacy and long-term safety study of firibastat (QGC001) 1000 mg (2500 mg tablets) administered po, QD, for up to 48 weeks in patients with difficult-to-treat/treatment-resistant HTN. Subjects will continue to take their chronic antihypertensive therapies (at least 2 classes of antihypertensive therapies) …

antihypertensive drugs
hypertension
resistant hypertension
blood pressure diastolic
  • 0 views
  • 28 Sep, 2021
  • 2 locations
Sacubitril/Valsartan in Resistant Hypertension

The present study aims to evaluate the antihypertensive effect of sacubitril/valsartan in patients with resistant hypertension compared to the use of recommended and optimized antihypertensive

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects (DTC/RHS)

A randomized, double-blind, placebo-controlled multiple ascending dose study in hypertensive subjects on stable doses of at least three hypertensive drugs for at least 6 weeks prior to Screening. The study will consist of screening, PK-unit admittance, and safety follow up periods. Subjects will be randomized at a 6:2 ratio of …

  • 0 views
  • 27 Apr, 2022
  • 4 locations
Controlling and Lowering Blood Pressure With the MobiusHD™ (CALM-DIEM)

To perform post-market surveillance and evaluate the performance of the MobiusHD System in subjects with primary resistant hypertension.

antihypertensive drugs
hypertension
resistant hypertension
  • 2 views
  • 13 Jun, 2022
  • 14 locations
RADIANCE Continued Access Protocol (RADIANCE CAP): A Study of the ReCor Medical Paradise System in Clinical Hypertension (RADIANCE CAP)

RADIANCE CAP is a non-randomized study designed to allow for continued access to ultrasound renal denervation therapy via the Paradise System, and to allow for the on-going collection of safety and effectiveness data in subjects with uncontrolled hypertension despite the prescription of antihypertensive medications.

antihypertensive drugs
hypertension
uncontrolled hypertension
renal angiogram
  • 0 views
  • 23 Sep, 2022
  • 10 locations
Spironolactone in CKD Enabled by Chlorthalidone: PILOT (SPICE PILOT)

cardiovascular (CV) disease. Spironolactone (SPL), a mineralocorticoid receptor antagonist, is widely used to treat resistant hypertension, however one of the most common side effects is an increase of serum

antihypertensive drugs
hypertension
ace inhibitor
  • 0 views
  • 23 Mar, 2022
  • 1 location
Effects of Adrenal Artery Ablation and Spironolactone in Patients With Primary Aldosteronism

Primary aldosteronism (PA) is one of the most common cause of endocrine and resistant hypertension. Current studies have shown that the activation of the renin-angiotensin-aldosterone system

congenital adrenal hyperplasia
resistant hypertension
aldosterone
hypertension
captopril
  • 0 views
  • 24 Jan, 2021
  • 1 location