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Found 129 clinical trials
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A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors

A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors

  • 136 views
  • 08 Nov, 2020
  • 1 location
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma

boost of radiotherapy to the residual tumour will be delivered immediately after the end of the cRT. Stratum 3 This stratum is designed as a phase II trial to evaluate the benefit of

  • 25 views
  • 24 Jan, 2021
  • 62 locations
Boost Use in Breast Conservation Radiotherapy

This is a two arm randomized study for patients who are undergoing radiotherapy following breast conservation surgery for breast cancer. Local recurrence of breast cancer will be compared for patients receiving boost or no boost radiotherapy.

ductal carcinoma in situ
ductal carcinoma
carcinoma in situ
carcinoma
cancer
  • 18 views
  • 07 Nov, 2020
  • 1 location
Observation Combination Chemotherapy Radiation Therapy and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving combination chemotherapy may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. An autologous stem cell transplant may …

stem cell transplantation
melphalan
iobenguane
topotecan
doxorubicin
  • 30 views
  • 07 Nov, 2020
  • 28 locations
Uracil and Tegafur/Leucovorin (UFT/LV) Versus UFT/LV+ Polysaccharide-K (PSK) for Stage IIIa/IIIb Colorectal Cancer

undergone curative surgery without residual cancer using 3-year disease free survival (DFS) as the primary endpoint, and also to analyze the 3-year overall survival (OS), compliance, adverse

calcium
rectal carcinoma
adenocarcinoma
platelet count
leucovorin
  • 4 views
  • 07 Nov, 2020
  • 1 location
The IPLA-OVCA Trial Intra-Peritoneal Local Anaesthetics in Ovarian Cancer

eradicating tumours but, paradoxically, also for proliferation and invasion of residual cancer cells. It increases the shedding of malignant cells into the blood and lymphatic circulations, inhibits their

cytoreductive surgery
fallopian tube
metastasis
cancer of the ovary
ovarian cancer stage
  • 0 views
  • 30 Jan, 2021
  • 1 location
Phase 3 Trial Evaluating Hyperthermic Intraperitoneal Chemotherapy in Upfront Treatment of Stage IIIC Epithelial Ovarian Cancer

Aim of the Study is to compare two-years disease-free survival of Cytoreductive Surgery (CRS) and Hyperthermic IntraPEritoneal Chemotherapy (HIPEC, CDDP+Paclitaxel) vs CRS alone in Stage IIIC unresectable epithelial tubal/ovarian cancer with partial or complete response after 3 cycles of 1st line chemotherapy (CBDCA +Paclitaxel).

intraperitoneal chemotherapy
cancer chemotherapy
paclitaxel
cytoreductive surgery
cancer of the ovary
  • 67 views
  • 08 Nov, 2020
  • 2 locations
TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer

The purpose of this trial is to compare two different treatments for fit patients with head and neck cancer: All patients are given induction-chemotherapy (docetaxel, cisplatin, 5-FU). Subsequently patients are being randomised into two groups: - The first group receives neo-adjuvant chemotherapy ('high' dose cisplatin) and conventional radiotherapy - The …

chemoradiotherapy
dental caries
immunomodulator
fluorouracil
measurable disease
  • 10 views
  • 07 Nov, 2020
  • 1 location
First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)

The HL-Russia-1 is a non-randomized, open-label, multicenter, phase III, 3-arm study. The primary objective is to assess efficacy, safety and progression-free survival (PFS) of different approaches (earle favorable, early unfavorable and advanced stages) to first line chemotherapy for classical Hodgkin Lymphoma (HL).

  • 0 views
  • 27 Jan, 2021
  • 1 location
Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling

This is a prospective, single arm, open label, multicenter interventional study designed to evaluate the efficacy of neoadjuvant chemotherapy with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determined by the Celcuity CELx HER2 Signaling Function (HSF) testing.

invasive breast cancer
platelet count
doxorubicin
progesterone receptor
neutrophil count
  • 8 views
  • 21 Apr, 2021
  • 42 locations