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Found 376 clinical trials
Featured trial
Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Background: Chronic lymphocytic leukemia (CLL) is a cancer of white blood cells. It is also called small lymphocytic lymphoma (SLL). It causes tiredness, night sweats, weight loss, swollen lymph nodes, easy bruising or bleeding, and frequent infections. Researchers want to test if a drug combination is effective and safe for …

fludarabine
fatigue
night sweats
TP53
cancer
  • 359 views
  • 23 Nov, 2020
  • 1 location
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.

  • 0 views
  • 23 Apr, 2022
  • 1 location
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma

months and < 22 years at diagnosis, with residual disease to investigate the possible activity of HD-MTX by giving to all patients the benefit of VEC chemotherapy whilst randomising half of patients

  • 53 views
  • 21 Oct, 2021
  • 64 locations
Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

In this study, the investigators are hypothesizing that daratumumab-hyaluronidase will effectively treat T-ALL in patients who have persistent or recurrent MRD following treatment with chemotherapy.

  • 0 views
  • 09 Jul, 2022
  • 1 location
  • 2 views
  • 26 Jan, 2021
  • 1 location
Drug-Coated Balloon Coronary Angioplasty Versus Stenting for Treatment of Disease Adjacent to a Chronic Total Occlusion.

Drug-Coated-Balloon treatment or stenting of adjacent residual disease to the CTO body. The aim of this study is to investigate whether treatment with DCB is non-inferior to complete stenting of the

  • 1 views
  • 22 Aug, 2021
  • 2 locations
Tocilizumab in Active Moderate-severe Graves' Orbitopathy

proportion of patiens with inactivation and reactivation of disease (Primary Objective) Effect of therapy on disease progression, improvement of QoL, the degree of residual disease after the inflammatory

  • 1 views
  • 16 May, 2021
  • 4 locations
CAR-T Cell Therapy Targeting to CD19 for R/R ALL

producing CAR T cells targeting CD19, and to analyze the outcome of enrolled B-cell ALL patients with active disease or persistent residual disease.

  • 0 views
  • 03 Feb, 2022
  • 1 location
Study of Magrolimab Combinations in Participants With Myeloid Malignancies

incomplete hematologic recovery (CRi) (CR/CRi) (Phase 2 Cohort 2) and to evaluate the efficacy of magrolimab in combination with anti-leukemia therapy CC-486 as determined by the minimal residual disease

  • 0 views
  • 07 Jul, 2022
  • 17 locations
Development of Ovarian Tissue Autograft in Order to Restore Ovarian Function

ovarian tissue cryopreservation and after autograft when achieved. In cases of neoplastic malignancies, minimal residual disease detection will be performed on ovarian tissue, to avoid any risk of cancer

  • 6 views
  • 04 Feb, 2021
  • 2 locations