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Found 14 clinical trials
Examination of Idiopathic Hypogonadotropic Hypogonadism (IHH)and Kallmann Syndrome (KS)

The purpose of the study is to examine how Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism (IHH) affect reproductive hormones. These disorders are caused by a defect in

sex hormones
testosterone level
hypogonadism
idiopathic hypogonadotropic hypogonadism
hormone released
  • 85 views
  • 27 Jan, 2021
  • 1 location
Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer

may be partly attributable to the degree by which the assisted reproductive treatment affects the maternal hormonal environment, when the corpus luteum is a major source of reproductive hormones. On

  • 0 views
  • 22 Feb, 2021
  • 1 location
Reproductive Hormones During Sustained Administration of Kisspeptin

We want to find out what happens to reproductive hormone levels; Luteinising Hormone (LH), Follicle Stimulating Hormone (FSH), testosterone and oestradiol when kisspeptin is administered to people for a period of 8 days each month, using either placebo (saline) or kisspeptin in doses of 0.1, 0.3 or 1.0 nmol/kg/hour.

  • 134 views
  • 23 Jan, 2021
  • 1 location
Administration of Kisspeptin to Subjects With Reproductive Disorders

of reproductive hormones. The investigators hypothesize that kisspeptin administration will be a useful tool for characterizing certain reproductive disorders.

kisspeptin
screening procedure
reproductive hormones
replacement therapy
secondary hypogonadism
  • 806 views
  • 28 Jan, 2021
  • 1 location
Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss

The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular

hormonal contraception
regular menstrual cycles
reproductive hormones
polycystic ovary syndrome
insulin
  • 247 views
  • 26 Jan, 2021
  • 1 location
Neuropeptides in Human Reproduction

opioid hormone that is blocked by naloxone. We hypothesize that naloxone, by blocking dynorphin, will stimulate production of GnRH and kisspeptin, 2 other naturally occurring reproductive hormones

hypogonadism
kisspeptin
gonadotropin
screening procedure
reproductive hormones
  • 98 views
  • 27 Jan, 2021
Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling

produce other reproductive hormones. However, giving someone a continued amount of kisspeptin over a period of time can have the opposite effect and tell the body to, for a short time, stop making

estradiol
kisspeptin
secondary hypogonadism
screening procedure
reproductive hormones
  • 13 views
  • 28 Jan, 2021
  • 1 location
Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model

The proposed study involves experimentally manipulating reproductive hormones in nonpregnant, euthymic women to create a scaled down version of the changes that occur during pregnancy and the

postpartum depression
structured clinical interview
perinatal depression
functional magnetic resonance imaging
psychiatric disorder
  • 5 views
  • 02 Mar, 2021
  • 1 location
Impact of Estradiol on Endothelial Function in Peri-Menopausal Women

The purpose of this study is to identify the impact of estradiol (E2) on the mechanisms that regulate vascular endothelial function in peri-menopausal (PERI) women. This study is the first step in understanding factors contributing to endothelial dysfunction in women with advancing reproductive age and in response to E2 administration.

  • 0 views
  • 13 Feb, 2021
  • 1 location
Ketamine to Prevent PPD After Cesarean

The investigators plan to randomise participants to receive ketamine or placebo control subcutaneously or by 40-minute intravenous infusions and will follow them up for 42 days to assess the incidence of postpartum depression. This feasibility pilot study is designed to explore the adequacy of the study procedures and tolerability of …

  • 0 views
  • 26 Jan, 2021
  • 1 location