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Found 108 clinical trials
Renin and Renal Biomarker Response to Angiotensin II

patients requiring continuous renal replacement therapy, those with altered angiotensin I: angiotensin II ratios, and most recently, those with elevated renin levels (which may serve as a surrogate for

vasopressor
  • 4 views
  • 10 Dec, 2021
  • 1 location
The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans

The primary objective is to examine the impact of the Renin-Angiotensin-Aldosterone System (RAAS) blockade with medications (valsartan) or RAAS and neprilysin inhibition (valsartan/sacubitril

plasma glucose
metabolic syndrome
aldosterone
glycosylated hemoglobin
tolerance test
  • 336 views
  • 27 Feb, 2022
  • 1 location
Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

The aim of this cross-over trial is to assess aliskiren, a direct renin inhibitor, as a novel treatment to block complement activation in the kidneys and thereby attenuate renal disease and

mammogram
kidney biopsy
enzyme inhibitor
  • 17 views
  • 22 Mar, 2022
  • 1 location
Correlation Between Vitamin D and Symptoms Severity of Autonomic Nervous Mediated Syncope Child and it 's RAAS

children ; autonomic nervous mediated syncope; vitamin D ; symptom score ; renin-angiotensin-aldosterone-system

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 1 location
Effect of Fimasartan on Extended RAS and Vascular Functions in Patients With Type 2 Diabetes and Hypertension

In this study, we will assess the change of extended renin-angiotensin system including serum ACE-2 and angiotensin(1-7) levels and subclinical atherosclerosis after using fimasartan (an ARB

hemoglobin a1c
fimasartan
angiotensin
amlodipine
renin
  • 0 views
  • 08 Jan, 2022
  • 1 location
Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies (PROERCAN01)

This study evaluates the effect of renin-angiotensin blockers on chronic kidney disease progression in elderly (>65 years old) patients with non-proteinuric nephropathies. Half of the

angiotensin
antihypertensive
nephropathy
amlodipine
chronic kidney disease
  • 24 views
  • 23 Jan, 2021
  • 1 location
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis (PRECISION-BP)

circulating levels of NPs and elevated renin hormone (a part of the Renin-Angiotensin-Aldosterone System [RAAS]) at nighttime may contribute to the high nocturnal blood pressure in obese individuals which

Accepts healthy volunteers
  • 0 views
  • 19 Jun, 2022
  • 1 location
Effect of Olmesartan on Angiotensin(1-7) Levels and Vascular Functions in Diabetes and Hypertension (Ang(1-7))

In this study, we will assess the change of serum ACE-2, angiotensin(1-7), and vascular function after using olmesartan (an ARB), compared to conventional anti-hypertensive drug, amlodipine in hypertensive patients with T2DM.

angiotensin
amlodipine
hypertension
diabetes
blood pressure diastolic
  • 0 views
  • 21 Mar, 2022
  • 1 location
Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Chlorthalidone (CTD) may produce various metabolic disturbances, including hypokalemia, activation of Renin-Angiotensin- Aldosterone (RAA) system, oxidative stress, dyslipidemia, Fibroblast

metabolic syndrome
potassium
aldosterone
angiotensin
dyslipidemia
  • 24 views
  • 21 Mar, 2022
  • 3 locations
Effect of Reducing Sedentary Behavior on Blood Pressure (RESET-BP)

monitoring will be leveraged in the analysis of ABP to account for recent activity and posture and will inform adherence and dose-response relationships.We will also measure plasma renin activity and

self monitoring
aldosterone
diastolic blood pressure
systolic blood pressure
blood pressure diastolic
  • 55 views
  • 17 Feb, 2022
  • 1 location