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Found 292 clinical trials
Tranexamic Acid for Acute Upper Gastrointestinal Bleed in Cirrhosis

The management of acute upper gastrointestinal bleeding (UGIB) is challenging in patients with cirrhosis, as it is responsible for severe complications and high mortality rates. Fibrinolytic activity of the epithelial surfaces and of the submucosal blood vessels may interfere with hematemesis and even delay healing of ulcers. Tranexamic acid (TXA) …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial

The Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty (TKA): Multi-Center Trial is a study that will compare the effectiveness of various perioperative strategies for antibiotic delivery as prophylaxis for periprosthetic joint infections (PJI) and surgical site infection in elective primary TKA. The investigators hypothesize that a single dose …

total knee replacement
osteoarthritis
inflammatory arthritis
cefazolin
  • 115 views
  • 28 Feb, 2021
  • 20 locations
Angiotensin in Septic Kidney Injury Trial

The purpose of this study is to determine the effect of a systemic infusion of angiotensin II on haemodynamics and urine output in critically ill patients with severe sepsis/septic shock and acute renal failure. It will also help determine the feasibility of conducting a definitive and adequately powered randomised controlled …

abnormal renal function
renal failure
renal injury
renal replacement
angiotensin ii
  • 28 views
  • 07 Nov, 2020
  • 2 locations
Erythropoietin Role in Acute Kidney Injury

The use of erythropoietin to treat anemia in acute kidney injury (AKI) is controversial. No previous clinical trial has assessed the possible reduction of transfusions when erythropoietin is

erythropoietin
  • 531 views
  • 26 Jan, 2021
  • 1 location
Prevention of Akute Kidney Injury Hearttransplant ANP

Prospective, blinded, placebo-controlled trial. Patients: Adult patients (>18 years of age) undergoing de novo Htx, with a preoperative GFR > 30ml/min, not receiving an ABO-incompatible organ with an ischemia time of > 6 hours. A donor age > 70 years is an exclusion criteria. Intervention: Infusion of h-ANP fore five …

ischemia
renal injury
  • 2 views
  • 24 Jan, 2021
  • 1 location
Preventing Acute Kidney Injury (AKI) in Neonates

function and the attenuation of renal injury in newborns, and young infants following cardiac palliative/correction surgery. The study rationale is Aminophylline and theophylline are competitive non

  • 0 views
  • 23 Jan, 2021
  • 1 location
Anesthesia and Acute Kidney Injury After Nephrectomy

This study investigates the influence of type of anesthesia on postoperative renal dysfunction in patients undergoing nephrectomy. The participants will be allocated to either the group receiving the total intravenous anesthesia (TIVA) using propofol or the group receiving the inhaled anesthetics using desflurane.

  • 0 views
  • 25 Jan, 2021
Standard Versus Comprehensive Care for Post Acute Kidney Injury

The investigators aim to compare between standard versus comprehensive care for post-acute kidney injury who are admitted with acute kidney injury at least stage 2 or receive renal replacement

renal replacement therapy
renal injury
renal replacement
replacement therapy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Assessment of ProEnkephalin to Detect Acute Kidney Injury (AKI)

Researchers are observing the values of proEnkephalin (PENK) via a blood draw in hospitalized patients that are volume overloaded requiring diuresis. If changes in PENK are found, physicians may predict values of change in kidney function during treatment.

diuretics
edema
fluid overload
orthopnea
acute renal failure
  • 0 views
  • 25 Jan, 2021
  • 1 location
Mild Hypothermia and Acute Kidney Injury in Liver Transplantation

Acute kidney injury (AKI), or worsening kidney function, is a common complication after liver transplantation (20-90% in published studies). Patients who experience AKI after liver

nephropathy
liver transplant
anesthesia
chronic disease
chronic kidney disease
  • 38 views
  • 25 Jan, 2021
  • 3 locations