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Found 297 clinical trials
Mechanisms for Organ Dysfunction in Covid-19

The study aims to investigate organ dysfunction and biomarkers in patients with suspected or verified COVID-19 during intensive care at Uppsala University Hospital.

  • 25 Jan, 2021
  • 1 location
A Multicenter Observational Study on Safety of the Herbal Medicines at Inpatient Setting

Prospective observations on safety of the herbal medicines regarding liver and kidney injuries at inpatient setting of four sites in South Korea which are located at each quadrant of the country. In a previous study (PMID 28634823), six women presented liver injuries by herbs and similar findings were also reported. …

  • 05 Mar, 2021
Early Detection of Progressive Kidney Disease in Preterm Infants

central hypothesis of this clinical trial is that a subgroup of patients born preterm and of low birth weight will demonstrate early markers of kidney injury including elevated serum cystatin C

adult disease
cystatin c
renal injury
  • 28 Jan, 2021
  • 1 location
Rare Kidney Stone Consortium Biobank

This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent disease, and from their family members, for use in future research.

  • 24 Jan, 2021
  • 1 location
Prognostic Value of Lung Ultrasound in ST Segment Elevation Acute Myocardial Infarction (LUS-AMI)

The purpose of this study is to asses the prognostic value of lung ultrasound in patients with ST-segment elevation acute myocardial infarction.

myocardial infarction
  • 25 Jan, 2021
Prognostic Value of Flow-mediated Dilation in Hospitalized COVID-19 Patients

This study will evaluate the associations between vascular parameters and clinical outcomes in patients hospitalized with COVID-19. The vascular function and structure of individuals with COVID-19 admitted to the General Hospital of the University of Sao Paulo will be assessed in the first 72 hours of hospitalization. Then, participants will …

  • 27 Jan, 2021
  • 1 location
Myval European Study of Myval THV System Implanted in Patients With Native Severe Aortic Valve Stenosis.

Myval European Study: A retrospective, multicentre, observational study in patients presenting with native severe aortic valve stenosis and treated with Myval Transcatheter Heart Valve System in real-world setting.

  • 02 Feb, 2021
  • 2 locations
Markers of Tissue Injury and Rhabdomyolysis in Patients With Major Trauma

Major trauma is associated with a release of alarmins (DAMPs - damage-associated molecular patterns) from the injured tissues. This process results in the activation of the immune system, which is one of the main mechanisms participating in the development of organ dysfunctions in patients with major trauma.

  • 25 Jan, 2021
  • 1 location
Natural History and Structural Functional Relationships in Fabry Renal Disease Treatment Outcomes(Changes)in Fabry Renal Disease Study

The investigators will perform a study with two major components. The first is a natural history study of untreated Fabry patients. This study component will detail kidney microscopic structural changes in Fabry patients before starting enzyme replacement therapy and will correlate these changes with kidney function, including glomerular filtration rate …

renal function
replacement therapy
  • 26 Jan, 2021
  • 2 locations
Endothelial Function Inflammation and Organ Dysfunction in COVID-19

COVID-19 is a rapidly evolving pandemic with approximately 5% of all patients which require intensive care unit admission. In critically ill patients infected with COVID-19, approximately 15% had severe shock requiring medications to increase blood pressure. It appears that blood vessel tone is altered and microcirculation is not well regulated …

  • 26 Jan, 2021
  • 1 location