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Found 299 clinical trials
(Revival) Study to Investigate the Efficacy and Safety of Alkaline Phosphatase in Patients With Sepsis-Associated AKI

Clinical phase 3 study to investigate the effect of recAP on 28 day mortality in patients admitted to the ICU with acute kidney injury that is caused by sepsis. The study has three

  • 27 Jan, 2021
  • 1 location
Safety and Diagnostic Efficacy of Mangoral in Participants With Focal Liver Lesions and Reduced Kidney Function

The overall objective of this study is to evaluate the safety and diagnostic efficacy of Mangoral in liver MRI in participants with known or suspected focal liver lesions and severe renal impairment. The diagnostic efficacy of Mangoral will be assessed in terms of visualization of detected focal liver lesions in …

  • 23 Jul, 2021
  • 53 locations
Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)

Extracorporeal membrane oxygenation (ECMO) is of great value in supporting patients with cardiac shock. More than 80% ECMO patients will develop renal catastrophe that continuous renal replacement therapy (CRRT) is required. The evidence is conflict as to whether early CRRT improves outcomes. Early CRRT before a definite indication developed may …

  • 23 Jan, 2021
  • 1 location
Cisplatin Disposition and Kidney Injury

to the kidneys, and 3) whether a person's genetic make-up can increase or decrease the likelihood of kidney injury due to cisplatin therapy.

  • 25 Jan, 2021
  • 2 locations
Cerebral Microembolism in the Critically Ill With Acute Kidney Injury

generation in a cohort of critically ill patients with dialysis-dependent acute kidney injury.

  • 26 Jan, 2021
  • 1 location
Early Goal Directed Therapy for Acute Kidney Injury

Early goal directed therapy during 6 hours after occurence of the early phase of acute kidney injury

  • 07 Nov, 2020
  • 1 location
CytoSorb Reduction of FREee Hemoglobin/Acute Kidney Injury (AKI) During Cardiac Surgery

Prospective, multi-center, randomized, blinded, pivotal clinical study. Subjects will be randomized in a 1:1 ratio to either standard of care (SOC) alone or standard of care plus treatment with the CytoSorb device.

  • 09 Apr, 2021
  • 25 locations
CRP-Apheresis for Attenuation of Pulmonary MYocardial and/or Kidney Injury in COvid-19

The 'CAPMYKCO' study is a randomized controlled, open-label, single center proof of concept trial. The aim of this study is to evaluate whether a CRP-apheresis in addition to the current standard therapy is intended to mitigate the severity of the disease course of SARS-CoV-2, especially with regard to tissue injury …

  • 04 Jun, 2021
  • 1 location
KDIGO Bundle to Prevent AKI in Sepsis

(KDIGO) guidelines for AKI) of patients diagnosed with sepsis and abdominal post-surgical septic shock with positive results in the risk determination of acute renal injury by NephroCheck Test that

  • 25 Jan, 2021
  • 1 location
Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy

The purpose of this study is to determine whether sodium bicarbonate is effective in reducing kidney injury that may occur during cardiac surgery.

renal injury
cardiopulmonary bypass
heart surgery
glomerular filtration rate
  • 07 Nov, 2020
  • 1 location