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Found 1452 clinical trials
The Impact of Phosphate Metabolism on Healthy Aging

Determine the association between duration and dose of chronic conventional therapy with Pi and renal (nephrocalcinosis/nephrolithiasis), vascular (endothelial function), and cardiovascular function (echo- cardiography) in patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH) and patients with X-linked hypophosphatemia (XLH).

x-linked hypophosphatemia
  • 23 May, 2022
  • 1 location
Perceptions of LARC Among AYA With Chronic Illness (LARC)

The investigators aim to perform a qualitative study exploring attitudes and perceived barriers to Long Acting Reversible Contraception (LARC), both implants and IUDs, among adolescent and young adults (AYA) with chronic illness at CHLA. While the literature examining barriers to LARC uptake is growing, its focus has been on older …

  • 10 May, 2022
  • 1 location
Heidelberg Study on Diabetes and Complications (HEIST-DiC)

The prospective observational study entitled "Heidelberg Study on Diabetes and Complications" is designed to Monitor the presence and development of diabetic complications in type 1 and type 2 diabetic patients, as well as pre-diabetics. Mail Goal is to detect new metabolic mechanisms or new risk factors for the development of …

type 2 diabetes mellitus
hemoglobin a1c
oral glucose tolerance test
  • 24 Feb, 2022
Optimizing CO2 Injection Technique for EVAR

Automated carbon dioxide (CO2) angiography is considered a safe diagnostic alternative to standard iodinated contrast medium (ICM) for endovascular aortic repair (EVAR) of abdominal aortic aneurysm (AAA), especially in patients with preoperative renal function impairment. Recent literature experiences describe the use of automated CO2 angiography in EVAR. One of the …

  • 26 Apr, 2022
  • 1 location
The Effect of Tranexamic Acid in Total Blood Loss During Proximal Femoral Nailing

Blood loss is an important issue following intertrochanteric femoral fracture and may lead to requiring blood transfusions and transfusion complications. Tranexamic acid is a commonly used drug to decrease blood loss and the number of transfusions. The aim of our study is to determine the effectiveness of tranexamic acid use …

  • 14 May, 2022
Progression and Etiology of Cortical Porosity in Diabetic Bone Disease (PREPT2D)

Type 2 diabetes is associated with increased cortical bone porosity and increased fracture risk. The goal of this proposed study is to understand the longitudinal evolution of cortical bone porosity and to investigate the underlying biological processes that drive increased cortical porosity and fracture risk in the setting of diabetes. …

hemoglobin a1c
Accepts healthy volunteers
body mass index
  • 13 Jun, 2022
  • 1 location
Tempus Priority Study: A Pan-tumor Observational Study

Observational study that will be collecting clinical and molecular health information from cancer patients who have received comprehensive genomic profiling and meet the specific eligibility criteria outlined for each cohort with the goal of conducting research to advance cancer care and create a dataset that furthers cancer research.

hematologic malignancy
  • 30 May, 2022
  • 8 locations
Prognostic Observation of Posterior Reversible Encephalopathy Syndrome (POPRES)

Posterior Reversible Encephalopathy Syndrome (PRES) is a clinical-radiological entity, which is associated with a variety of clinical conditions. The imaging and clinical findings are typically reversible, but many patients still have permanent neurological sequelae with a fatal outcome. Up to now there are no consistent conclusions about the factors that …

  • 15 Mar, 2022
  • 1 location
Bone Density and Vascular Calcifications Evolution After Renal Transplant

The investigators project is based on: Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA); The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time; Longitudinal evaluation of nephrological …

  • 24 May, 2022
  • 1 location
Familial Investigations of Childhood Cancer Predisposition (SJFAMILY)

NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll. If you are interested in clinical testing please consider seeing a local genetic …

childhood cancer
genetic testing
familial cancer
biological factors
  • 25 May, 2022
  • 1 location