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Found 22 clinical trials
A Randomized Controlled Trial Comparing Imipenem and Tigecycline Versus Imipenem and Tigecycline With GM-CSF for the Management of Spontaneous Bacterial Peritonitis Presenting With Septic Shock.

> Haemoglobin, Total peripheral leucocyte counts, Platelet counts, Renal function tests Liver function tests and Chest X rays will be undertaken

  • 0 views
  • 24 Feb, 2021
  • 1 location
Evaluate the Efficacy and Safety of Short-term Administration of SIMDAX

A randomized, double-blind, Multicenter, parallel, placebo-controlled study

  • 0 views
  • 16 May, 2021
  • 1 location
Impact of Amantadine on Traumatic Brain Injury

The aim of this study is to evaluate whether the addition of amantadine to the management regimen of traumatic brain injury patients would have a favorable effect on recovery and neurological complications in association with prognosis biomarkers Interleukin-18 (IL-18), Neuron-specific enolase (NSE) and (Neurotensin).

  • 0 views
  • 01 Feb, 2021
  • 1 location
Prosthetic Femoral Access for Haemodialysis

This study will compare the outcomes of tunneled femoral catheter and femoro-femoral arteriovenous graft as a bailout procedure for hemodialysis in chronic kidney disease patients with exhausted upper-extremity and chest-wall vascular accesses regarding survival rate, complications, and quality of life

  • 0 views
  • 19 Feb, 2021
  • 1 location
Dexamethasone Compared to Non-steroidal Anti-inflammatory Drugs in the Treatment of Acute Pericarditis

The treatment of acute pericarditis is empiric and is based on treatment with medications with anti-inflammatory properties such as non-steroidal anti-inflammatory drugs (NSAID) and corticosteroids. However, this therapy is given as a relatively long course of therapy ( 3 weeks) and can be associated with substantial side effects. Dexamethasone is …

  • 0 views
  • 19 Mar, 2021
  • 1 location
Renal Function Assessment in the Elderly Using Plasma Creatinine Assay and Lean Body Mass Measurement

Glomerular filtration rate (GFR) is the recommended parameter to assess renal function. The reference technique to measure GFR (clearance of a glomerular agent) is not commonly used. Instead, estimations (eGFR) are routinely taken from serum creatinine (SCr) with several published formulae: Cockcroft and Gault, MDRD, CKD-EPI. Basically, all these formulae …

  • 0 views
  • 24 Jun, 2021
  • 1 location
The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function

Black individuals are at increased cardiovascular disease risk. The central goal of the study is to determine if mitochondrial reactive oxygen species influence blood vessel function and nervous system regulation of blood pressure differentially in black, compared to white individuals. These findings may help to explain a potential mechanism that …

hypertension
metabolic disorders
diabetes
cardiovascular disease
  • 52 views
  • 27 Jan, 2021
  • 1 location
Renal Effects of Hormones/Biomarkers in Transgender PrEP Recipients

Will use a subset of the main study cohort of transgender or non-binary individuals to evaluate the relationships between self-reported exogenous hormone use, endogenous hormone values, renal biomarkers, drug levels and directly measured renal function.

  • 0 views
  • 17 Feb, 2021
  • 1 location
Mesenchymal Stem Cells Transplantation for Refractory Systemic Lupus Erythematosus (SLE)

This study will explore a new approach to treat patients with a medical condition known as systemic lupus erythematosus (SLE) who have been resistant to previous treatments using a new population of cells with capability to restore a normal immune system that will no longer attack the body. The stated …

  • 30 views
  • 07 Nov, 2020
  • 1 location
Pharmacokinetics of Ledipasvir/Sofosbuvir in Hepatitis C Virus-Infected Children With Hematological Malignancy

This is a prospective, controlled, open-label, pharmacokinetic study. This study aims at studying the PK of ledipasvir, sofosbuvir, and GS-331007 metabolite in HCV infected children with hematological malignancy. In this study, patients in both treatment groups will receive 12 weeks of treatment with a xed-dose combination tablet containing 45 mg …

  • 0 views
  • 22 Jan, 2021
  • 1 location