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Found 330 clinical trials
Featured trial
Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB000928 in Participants With Impaired Renal Function and Hemodialysis

This is a multicenter, open-label parallel-group to evaluate single oral doses of INCB000928 in participants with varying level of renal function or impairment.

body mass index
Accepts healthy volunteers
renal function
  • 0 views
  • 04 Oct, 2022
  • 4 locations
Featured trial
Myelofibrosis

Myelofibrosis

  • 574 views
  • 08 Nov, 2020
  • 1 location
Sacubitril/Valsartan for CKD5 Stage Dialysis Patients With Heart Failure

function, renal function, blood pressure success rate, and adverse reactions of two groups, to evaluate whether the efficacy and safety of Sacubitril/Valsartan in the treatment of patients with CKD

  • 2 views
  • 12 Mar, 2022
Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure (HSS)

Acute Decompensated Heart Failure (ADHF).However, chronic treatment with diuretics may limit their response and deteriorates the renal function. The hypertonic saline solution (HSS) has been proposed in

  • 0 views
  • 18 Apr, 2022
  • 1 location
Twice Against Thrice-weekly Hemodialysis (TATH)

Hemodialysis is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. The frequency of sessions per week remains a debatable issue. In the majority of developed Western and Asian countries, patients on chronic hemodialysis are undergoing three dialysis sessions weekly. In developing countries and some developed …

renal replacement therapy
chronic renal failure
chronic hemodialysis
hypertension
  • 124 views
  • 26 Feb, 2022
  • 1 location
Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx (ConfIdeS)

An open-label, controlled, randomized Phase 3 trial evaluating 12-month kidney function in highly sensitized (cPRA ≥99.9%) kidney transplant patients with positive crossmatch against a deceased donor, comparing desensitization using imlifidase with standard of care

  • 0 views
  • 04 Oct, 2022
  • 10 locations
DAPAgliflozin Sodium Water glucosE EffecTs in Patients at High Cardiovascular Risk (DAPA-SWEET)

This study aims to elucidate the impact of SGLT2 inhibition on peripheral vascular function, renal function, fluid volume, neurohormonal activation and inflammatory/fibrotic pathways in patients

hba1c
type 1 diabetes mellitus
body mass index
diabetes
heart disease
  • 0 views
  • 25 Feb, 2022
Feasibility of Neo-adjuvant Versus Adjuvant Chemotherapy in Upper Tract Urothelial Carcinoma (URANUS)

(PS and renal function) who receive only standard treatment (Radical nephroureterectomy (RNU)). This comparison will be made using a uniform diagnostic and treatment protocol.

  • 1 views
  • 21 Apr, 2022
  • 17 locations
Follow-up During the Peripubertal Period of Preterm Children Included in the Protocol Entitled "EPIPOD". (INFANTPOD)

14 years, will be included in the INFANTPOD protocol. Analysis of body composition, insulin resistance, renal function, pulse wave velocity, eating behaviour and of neuropsychological

  • 0 views
  • 25 Mar, 2022
  • 1 location
Overnight Bladder Drainage and Posterior Urethral Valve Sequelae

We hypothesize that overnight catheter drainage (OCD) of the urinary bladder might improve bladder dynamics and subsequently lead to improvement or resolution of hydronephrosis (HN) and renal

  • 0 views
  • 30 Dec, 2021
  • 1 location