Found 390 clinical trials
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma
. Researchers want to see if this therapy fights kidney cancer cells. Metastatic renal cell carcinoma (RCC) is an incurable condition. Current therapy for this disease consists of the serial administration
- 210 views
- 22 Dec, 2020
- 1 location
AREN03B2: Study of Kidney Tumors in Young Patients
AREN03B2: Study of Kidney Tumors in Young Patients
- 36 views
- 08 Nov, 2020
- 1 location
AREN03B2: Renal Tumors Classification, Biology, and Banking Study
AREN03B2: Renal Tumors Classification, Biology, and Banking Study
- 106 views
- 08 Nov, 2020
- 1 location
A Phase 1/1b Study of Sitravatinib in Combination with Nivolumab and Ipilimumab in Patients with Advanced or Metastatic Clear-Cell Renal Cell Carcinoma or Other Solid Malignancies
Study 516-008 is an open-label Phase 1 dose escalation/Phase 1b dose expansion study evaluating the safety and tolerability, clinical activity, and PK of sitravatinib in combination with nivolumab and ipilimumab for the treatment of ccRCC and potentially other solid tumor types. Sitravatinib is a spectrum-selective receptor tyrosine kinase (RTK) inhibitor …
- 57 views
- 15 Sep, 2020
- 1 location
A Phase 1b, Dose-escalation Study of Pexa-Vec (Thymidine Kinase-Deactivated Vaccinia Virus Plus GM-CSF) in Combination With REGN2810 (Anti-PD-1) in Patients With Metastatic or Unresectable Renal Cell Carcinoma (RCC)
This is a Phase 1b, open-label, multi-center, dose-escalation trial of Pexa-Vec plus REGN2810 in patients with metastatic or unresectable renal cell carcinoma (RCC). The trial consists of a
- 2 views
- 23 Nov, 2020
- 3 locations
Alliance A031203: Randomized Phase II Study Comparing Cabozantinib (NSC #761968 and IND #116059) With Commercially Supplied Sunitinib in Patients With Previously Untreated Locally Advanced or Metastatic Renal Cell Carcinoma
Metastatic Renal Cell Carcinoma
- 206 views
- 08 Nov, 2020
- 1 location
A Multicenter, Open-Label, Randomized, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib in Combination with Everolimus or Pembrolizumab Versus Sunitinib Alone in First Line Treatment of Subjects with Advanced Renal Cell Carcinoma
Subjects with Advanced Renal Cell Carcinoma
- 222 views
- 25 Mar, 2021
- 1 location
Procurement of Human Biospecimens for Research
Procurement of Human Biospecimens for Research
- 53 views
- 23 Nov, 2020
- 1 location
Procurement of Human Biospecimens for Research
Procurement of Human Biospecimens for Research
- 80 views
- 23 Nov, 2020
- 1 location
A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma
The purpose of this study is to evaluate MEDI5752 in combination with Lenvatinib (or Axitinib), in subjects with advanced renal cell carcinoma.
- 28 views
- 05 Sep, 2023
- 15 locations