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Found 19 clinical trials
  • 0 views
  • 15 Sep, 2022
  • 6 locations
SOLIDARITY Finland Long-COVID (Remdesivir Long-term Follow-up Study of COVID Patients)

SOLIDARITY Finland Long-COVID trial assesses the effects of remdesivir + standard of care (SoC) vs. only SoC on long-COVID symptoms and quality of life (QoL) using questionnaires at one and two

  • 0 views
  • 23 Jul, 2022
  • 1 location
Clinical Experimentation With Tenofovir Disoproxyl Fumarate and Emtricitabine for COVID-19

Clinical, control, double-blind, randomized trial with tenofovir disoproxyl fumarate and emtricitabine for Covid-19

  • 0 views
  • 01 Feb, 2021
  • 1 location
A Phase 2/3 Single-Arm, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Remdesivir (GS-5734™) in Participants From Birth to < 18 Years of Age With COVID-19 (CARAVAN)

The primary objectives of this study are to evaluate the safety, tolerability, and pharmacokinetics (PK) of remdesivir (RDV) in participants with laboratory-confirmed coronavirus disease 2019

remdesivir
covid-19
coronavirus infection
SARS
  • 380 views
  • 22 Sep, 2022
  • 27 locations
Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19

hospitalization and oxygen therapy, and up to 5% of patients require admission to Intensive Care Units. To date, the only treatments that have shown efficacy in a clinical trial are remdesivir and

  • 0 views
  • 29 May, 2021
  • 1 location
Finding Treatments for COVID-19: A Phase 2 Multi-centre Adaptive Platform Trial to Assess Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

The trial will develop and validate a platform for quantitative assessment of antiviral effects in low-risk patients with high viral burdens and uncomplicated COVID-19 to determine in-vivo antiviral activity. In this randomized open label, controlled, group sequential adaptive platform trial, we will assess the performance of three distinct types of …

  • 0 views
  • 14 Sep, 2022
  • 2 locations
I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, …

covid-19
remdesivir
critical illness
mechanical ventilation
SARS
  • 160 views
  • 30 Jul, 2021
  • 19 locations
Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

respiratory conditions and current smoking status. In May 2020, the FDA authorized the emergency use of remdesivir for treatment of COVID-19 disease based on topline date of two clinical trials, even though

acute respiratory distress
acute lung injury
covid-19
pneumonia
coronavirus
  • 0 views
  • 10 Jul, 2022
  • 2 locations
Low-dose Tocilizumab Versus Standard of Care in Hospitalized Patients With COVID-19 (COVIDOSE-2)

dose is critical. We conducted an open-label, randomized, controlled trial evaluating two different dose levels of tocilizumab in Covid-19 (40mg and 120mg). Randomization was stratified on remdesivir

tocilizumab
covid-19
chest radiograph
interleukin-6
fever
  • 0 views
  • 26 May, 2022
  • 1 location
SOLIDARITY Finland Plus Long-COVID

questionnaire will be the same that has been used in the SOLIDARITY Finland Long-COVID trial on remdesivir. The questionnaire was developed by our multidisciplinary team of physicians, including the

  • 0 views
  • 17 May, 2022
  • 1 location