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Found 32 clinical trials
OPTmizing Advanced Stage HodgkIn LymphoMa patIentS Therapy

This is a prospective, multi-center, open-label, phase II clinical trial, aims to assess the effectiveness of the combination ACVD (Adriamycin, Cyclophosphamide, Vinblastine and Dacarbazine) and BV (Brentuximab Vedotin) in PET-2 positive advanced-stage HL patients, in order to improve the overall long-term disease control in the entire cohort of advanced-stage HL.

adriamycin
brentuximab
vinblastine
lymphoma
dacarbazine
  • 6 views
  • 23 Jan, 2021
  • 1 location
Brentuximab Vedotin and BeEAM High-dose Chemotherapy in Lymphomas

The trial assess the maximum tolerated dose of a single-dose of Brentuximab Vedotin added to standard BeEAM chemotherapy (comprising Bendamustin, Etoposide, Cyclophosphamide and Melphalan) before autologous stem cell transplantation in CD30+ malignant lymphomas.

melphalan
cell transplantation
high dose chemotherapy
neutrophil count
solid tumor
  • 4 views
  • 26 Jan, 2021
  • 1 location