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Found 29 clinical trials
A Phase III, Randomized, Double-masked, Placebo-controlled, Parallel-group, Multicenter Study of the Safety and Efficacy of OT-101 (Atropine Sulfate 0.01%) in Treating the Progression of Myopia in Pediatric Subjects

This is a phase III, randomized, double-masked, placebo-controlled, parallel-group, multicenter safety, tolerability, and efficacy study of atropine sulfate 0.01% (OT-101) as an investigational treatment for myopia in pediatric subjects

  • 110 views
  • 16 Oct, 2022
  • 7 locations
A Randomized Trial of Low-Dose Bevacizumab Versus Laser for Type 1 Retinopathy of Prematurity (ROP3)

prematurity (ROP). The study also will assess neurodevelopment, refractive error, visual acuity, and peripheral visual fields.

  • 0 views
  • 24 Oct, 2022
  • 19 locations
Superior vs Temporal Laser Peripheral Iridotomy in Primary Angle Closure Suspects (PACS)

Basic Study Design: Prospective, randomized, single-center, single-blinded study to compare dysphotopsias and pain recollection immediately 2 weeks, and 3 months after LPI in PACS patients who have a clear indication for bilateral LPI. Our null hypothesis is that there is no difference in dysphotopsia or pain levels by LPI position. …

Accepts healthy volunteers
  • 0 views
  • 15 May, 2022
  • 1 location
Shanghai Eye Study for Adults (SESA)

uncorrected refractive error, of which, 62.1% can be solved through refractive correction. For this reason, the uncorrected refractive errors of 154,000 senior citizens in Shanghai can be taken as a priority

Accepts healthy volunteers
  • 57 views
  • 04 Jun, 2022
  • 1 location
Zimbabwe Eyecare And Learning(ZEAL):Formative Research on Hyperopia and Educational Outcomes in Primary School Children (ZEAL)

Mashonaland Central province of Zimbabwe, compared to age-, gender- and school-matched children with no refractive error (emmetropia), measured by the Happy Readers V4 reading tool over six months.

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Village-Integrated Eye Worker Trial II (VIEW II)

treatment. The leading causes of visual impairment are cataract and refractive error, followed by glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR). Loss of vision from these

macular degeneration
Accepts healthy volunteers
optical coherence tomography
visual impairment
diabetic retinopathy
  • 42 views
  • 10 Feb, 2022
  • 1 location
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits

Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course. It is essential to develop novel health care models, utilizing telemedicine, to improve the ability to detect glaucoma at an earlier stage, and to provide a platform …

glaucoma
Accepts healthy volunteers
diabetes
visual loss
eye disease
  • 0 views
  • 22 Apr, 2022
  • 1 location
Clinical Investigation of the CHEETAH SYSTEM FOR THE CORRECTION OF MYOPIC REFRACTIVE ERRORS WITH AND WITHOUT ASTIGMATISM

This study will be a 3-phase, 12-months, prospective,single arm, multicenter, open-label, non-comparative, clinical investigation conducted at up to 7 sites. Up to 20 subjects will be enrolled in phase I, up to 30 subjects in phase II, and up to 200 subjects in phase 3 to achieve up to 350 …

astigmatism
refractive error
subjective refraction
corrected visual acuity
myopia
  • 21 views
  • 27 Oct, 2022
  • 5 locations
Evaluating Contact Lens Optics

This study will evaluate changes in refractive error and visual performance between a single vision soft contact lens and multifocal soft contact lens

astigmatism
corrected visual acuity
refractive error
contact lens prescription
  • 0 views
  • 13 Mar, 2022
  • 1 location
Cataract Online Refraction Evaluation: A Multi Center Randomized Controlled Trial

ascertain no adverseevents have occurred immediately after surgery, and between 4-6 weeks, to determine the refractive error. The incidence of seriousadverse events following cataract surgery is estimated

  • 0 views
  • 04 Oct, 2022
  • 3 locations