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Found 183 clinical trials
Effect of a Combination Oral Formulation of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate in Patients With Gastro-Esophageal Reflux Disease Not Fully Satisfied With Their Treatment

This is a post-market, multi-center, double-blind, placebo-controlled, randomized, cross-over study with GERDOff Plus added on top of the current PPI treatment in patients with GERD. The aim of the study is to evaluate the performance of GERDOff Plus, a class III medical device, consisting in a hyaluronic acid, chondroitin sulphate …

endoscopy
  • 24 views
  • 15 May, 2022
  • 1 location
The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole

After vonoprazan (20mg/day) or esomeprazole (20mg/day) for 4weeks is prescribed for patients with erosive esophagitis diagnosed by esophagogastroduodenoscopy, the number of patients who will visit our outpatient clinic again due to some reasons without any appointments is compared with vonoprazan group and esomeprazole.

  • 0 views
  • 16 May, 2022
  • 1 location
The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity

Reflux hypersensitivity is the disease that causes chest pain, heartburn and regurgitation and can impair patients' quality of life. Pain modulators are often used for the treatment of reflux

esophagitis
heartburn
regurgitation
acidity
  • 62 views
  • 06 May, 2022
  • 1 location
Efficacy and Safety of Thread Embedding Acupuncture in Treating Gastroesophageal Reflux Disease

Gastroesophageal reflux disease is a very common disease nowadays. Proton-pump inhibitors (PPIs) are the first-line treatment for this disease. However, the effectiveness of treatment with PPIs

  • 0 views
  • 24 May, 2022
  • 1 location
Domiciliary Management of Dental Erosion in Patients With GERD With Biomimetic Hydroxyapatite

The aim of the present study is to evaluate dental erosion in patients with gastroesophageal reflux disease (GERD). Patients consenting to participate to the study will undergo

  • 0 views
  • 30 May, 2022
  • 1 location
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Vonoprazan in Adolescents With Symptomatic Gastroesophageal Reflux Disease

The primary objective of this study is to evaluate the pharmacokinetic profile of vonoprazan in adolescent participants with symptomatic gastroesophageal reflux disease (GERD).

  • 0 views
  • 04 Jun, 2022
  • 3 locations
Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repair

This single-blind randomized control study will follow 142 subjects across 5 sites randomized on a 1:1 ratio to compare treatment efficacy and safety between TIF and LNF in GERD patients with hiatal hernia undergoing hernia repair.

  • 0 views
  • 06 Aug, 2021
  • 5 locations
Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's Esophagus

To assess patient acceptance and preference among screening modalities, Esophagogastroduodenoscopy (EGD), Transnasal Esophagoscopy (TNE), and Cytosponge for Barrett's esophagus (BE). Subjects will undergo administration of Cytosponge and transnasal endoscopy (TNE) prior to their scheduled clinically indicated upper endoscopy performed per routine standard of care. Following the procedure, a follow-up phone …

gastroesophageal reflux
endoscopy
reflux
gastroscopy
esophagogastroduodenoscopy
  • 38 views
  • 18 Sep, 2021
  • 1 location
Crural Repair During Laparoscopic Sleeve Gastrectomy in Patients With a Lax Gastroesophageal Junction (REPAIR)

Background Laparoscopic sleeve gastrectomy (LSG) is one of the commonest bariatric procedures. However, it is associated with postoperative gastroesophageal reflux

sleeve gastrectomy
gastric bypass
  • 0 views
  • 05 May, 2022
  • 2 locations
Compassionate Use of Domperidone for Refractory Gastroparesis

The purpose of this program is to allow the use of domperidone in children from 12 to 21 years of age with symptoms related to motility disorders and Gastroesophageal reflux disease (GERD) who

  • 0 views
  • 09 Jun, 2022
  • 1 location