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Found 62 clinical trials
Ofatumumab as Part of Reduced Intensity Conditioning (RIC) Regimen for Patients With High Risk Chronic Lymphocytic Leukemia (CLL) Undergoing Allogeneic Hematopoietic Cell Transplantation

disease whose life expectancy is significantly reduced. As a result, reduced intensity conditioning (RIC) allogeneic hematopoietic cell transplantation (allo-HCT) has been investigated as a

anti-cd20 monoclonal antibody
bendamustine
graft versus host disease
rituximab
cancer
  • 12 views
  • 08 Nov, 2020
  • 2 locations
Allogeneic Hematopoietic Stem Cell Transplantation

To assess the engraftment of hematopoietic stem cells following reduced-intensity conditioning in children presenting with solid tumors or hematological malignancy by evaluating post

allogeneic transplantation
cell transplantation
myeloablative conditioning
fludarabine
busulfan
  • 18 views
  • 07 Nov, 2020
  • 1 location
Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma

This phase II trial studies how well a reduced intensity conditioning regimen after donor stem cell transplant works in treating patients with multiple myeloma that has come back (relapsed

cell transplantation
fludarabine
diffusion capacity of the lung for carbon monoxide
tacrolimus
ejection fraction
  • 0 views
  • 29 Mar, 2021
  • 1 location
Individualized Dose Study of ATG in Haploidentical Hematopoietic Stem Cell Transplantation

The purpose of this study is to determine the response and toxicity rate of two different dosages (Individualized dosage VS. fixed dosage) of ATG as a prophylaxis for acute GVHD in haploidentical peripheral blood stem cell transplantation (haplo-PBSCT).

  • 0 views
  • 12 Mar, 2021
  • 1 location
International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia

/cyclophosphamide and reduced intensity conditioning (RIC) with fludarabine/busulfan.

gilbert's syndrome
myeloablative conditioning
anthracyclines
ejection fraction
busulfan
  • 0 views
  • 26 Jan, 2021
  • 59 locations
Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant

This phase II trial studies how well ibrutinib works in preventing acute leukemia in patients after reduced-intensity conditioning and stem cell transplant. Ibrutinib may stop the growth of

gilbert's syndrome
myeloablative conditioning
filgrastim
tacrolimus
leukemia
  • 54 views
  • 24 Jan, 2021
  • 1 location
Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT BMT or PBSCT

The objective of this study is to evaluate the efficacy of using a reduced-intensity condition (RIC) regimen with umbilical cord blood transplant (UCBT), double cord UCBT, matched unrelated donor (MUD) bone marrow transplant (BMT) or peripheral blood stem cell transplant (PBSCT) in patients with non-malignant disorders that are amenable to …

  • 22 views
  • 25 Jan, 2021
  • 2 locations
Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS

The purpose of this study is to compare safety and efficacy of reduced-intensity conditioning and myeloablative conditioning regimens prior to HSCT in high-risk AML/MDS pediatric and young adult

gilbert's syndrome
myeloablative conditioning
fludarabine
aml/mds
leukemia
  • 36 views
  • 26 Jan, 2021
  • 1 location
Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders

This is a Phase II pilot study to evaluate engraftment and toxicity of patients with non-malignant diseases using a reduced intensity conditioning regimen in the setting of allogeneic transplant

reduced intensity conditioning
severe combined immunodeficiency
campath
transplant conditioning
shortening fraction
  • 1 views
  • 14 Mar, 2021
  • 1 location
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

This is a treatment guideline for a second or greater allogeneic hematopoietic stem cell transplant (HSCT) using a reduced intensity conditioning (RIC) in patients with non-malignant or

reduced intensity conditioning
myeloablative conditioning
total body irradiation
fludarabine
granulocyte colony stimulating factor
  • 17 views
  • 24 Jan, 2021
  • 1 location