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Found 77 clinical trials
Comparison of Obturator Nerve Block With Ultrasound Guidance and Anatomical Signs

Comparison of the obturator nerve block in patients undergoing transurethral resection due to bladder tumor, technically using ultrasound guided or blinded with anatomical signs.

bladder tumor
transurethral resection
  • 22 Mar, 2022
  • 1 location
LITT Followed by Hypofractionated RT for Recurrent Gliomas (GCCC 19140)

The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with recurrent gliomas.

karnofsky performance status
brain mri
recurrent tumor
treatment regimen
  • 25 Feb, 2022
  • 3 locations
Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

Objectives To determine intraperitoneal (IP) progression free survival after optimal debulking and heated intraperitoneal chemotherapy (HIPEC) with cisplatin in patients with IP spread of adrenocortical cancer. Determine morbidity of this procedure in this patient population. Determine the impact of surgery and HIPEC on quality of life (QOL) and hormone excess. …

peritoneal metastases
pet scan
optimal debulking
neutrophil count
lung metastases
  • 31 Jan, 2022
  • 1 location
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases

This early phase I trial tests the use of a radioactive tracer (a drug that is visible during an imaging test) known as 18F-FMAU, for imaging with positron emission tomography/computed tomography (PET/CT) in patients with brain cancer or cancer that has spread to the brain (brain metastases). A PET/CT scan …

  • 28 Mar, 2021
  • 1 location
Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy

This pilot clinical trial studies the side effects and best dose of radiation therapy in patients with brain tumors that have come back after previous treatment with radiation therapy. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving radiation therapy in different ways may kill …

tumor cells
karnofsky performance status
recurrent brain tumors
  • 24 Feb, 2022
  • 1 location
Research for the Molecular Imaging of the PD-L1 Targeting Tracer

To use the molecular probe PET radionuclide (Ga-68 or F-18) WL12 peptide to detect the expression of PD-L1 in the primary and metastatic lesions in patients with solid tumor; to detect the expression heterogeneity of PD-L1 in the lesion and inter-lesions; to observe the change of PD-L1 expression in the …

solid tumor
  • 25 Jan, 2021
  • 1 location
Salvage Chemoradiation Therapy for Recurrence After Radical Surgery or Palliative Surgery in Esophageal Cancer Patients

Currently, adjuvant therapy is not recommended for patients with esophageal squamous cell carcinoma who received radical surgery. However, the recurrence rate is as high as 23.8%-58%, and the median time-to-recurrence is about 10.5 months. In patients who had residual tumor after surgery, evidence lacks for chemoradiation. The aim of the …

esophagus cancer
esophageal cancer
squamous cell carcinoma of esophagus
  • 22 Jan, 2021
  • 1 location
Collagen Implant (Biological Mesh) Versus GM Flap for Reconstruction of Pelvic Floor After ELAPE in Rectal Cancer

The trial compares two different techniques for reconstruction of the lesser pelvic floor after an extended abdominoperineal excision for locally advanced rectal cancer. The alternative reconstruction techniques in the trial are: a technique using a gluteus maximus myocutaneous flap or a technique using an acellular porcine collagen implant (biological mesh) …

abdominoperineal resection
  • 18 Mar, 2021
  • 11 locations
Surgical Excision Versus Photodynamic Therapy and Topical 5-fluorouracil in Treatment of Bowen's Disease (BOWTIE)

There is limited quality research on the effectiveness of treatments in Bowen's disease (BD). Patient and lesion characteristics, patient preferences and costs should be considered when choosing therapy. Surgical excision (SE), photodynamic therapy (PDT) and 5-fluorouracil (5FU) are mentioned as treatment options in guidelines. However no clear and evidence based …

  • 15 Feb, 2022
  • 1 location
A Phase I Dose Escalation Study for Patients With Recurrent Malignant Gliomas

This is a clinical trial (a type of research study). Clinical trials include only patients who choose to take part. You are being asked to take part in this study because you have a brain tumor that continued to grow despite prior therapy. Currently, there is no known effective treatment …

  • 07 Nov, 2020
  • 1 location