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Found 77 clinical trials
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors

This study investiagates deep-regional or superficial hyperthermia to enhance radiotherapy or chemoradiation in patients that suffer recurrent disease after previous radiotherapy.

recurrent disease
  • 23 May, 2021
  • 1 location
Physical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Participants With Advanced, Metastatic, or Recurrent Cancer

The goal of this clinical research study is to learn about the effects of combining physical activity with dexamethasone to treat fatigue in patients with advanced cancer. In this study, dexamethasone will be compared to a placebo. A placebo is not a drug. It looks like the study drug but …

advanced cancer
  • 09 Mar, 2022
  • 1 location
Mobile-based Empathic Communication Support Program to Promote Advance Care Planning Discussion in Advanced Cancer Patients

. During the outpatient visit, patients and their physicians will be provided feedback based on the interview. Study subjects: In sum, 264 patients with advanced or recurrent cancer will be

  • 06 Oct, 2021
  • 1 location
"QUAD SHOT" Radiotherapy With Pembrolizumab in Patients With Recurrent Head & Neck Cancer (QUADSHOT)

The purpose of this study is to test the safety of palliative "QUAD SHOT" radiotherapy combined with pembrolizumab and evaluate the effects of the combination treatment patients with recurrent

neutrophil count
squamous cell carcinoma
cancer of the head
  • 23 Mar, 2022
  • 1 location
Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas

A pilot study to determine the safety and efficacy of chimeric antigen receptor T cell (autologous T cells transduced with a lentiviral vector expressing chimeric antigen receptor with or without anti-PDL1 antibody) personalized immunotherapy for patients with recurrent malignant gliomas based on the expression of tumor specific/associated antigens (EGFRVIII, IL13R2, …

karnofsky performance status
growth factor
malignant glioma
  • 26 Feb, 2022
  • 1 location
Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma

This is a phase 2 open-label study to test the safety and effectiveness of combining pembrolizumab and bendamustine in patients with relapsed (cancer that has come back or started getting worse) or refractory (cancer that is not responding or has stopped responding to treatment) Hodgkin lymphoma.

  • 22 Mar, 2022
  • 1 location
Impact of Human-Animal Interactions on Children With Life-Threatening Conditions and Their Parents

This study will evaluate the effects of human-animal interaction on reducing anxiety, depression, worry, and pain and enhancing quality of life in children ages 8-17 years old with a life threatening cancer and their parent caregivers.

Accepts healthy volunteers
  • 25 May, 2022
  • 1 location
HepatoPredict Prognostic Tool for the Decision of Liver Transplant in Hepatocellular Carcinoma (HepatoPredict)

Liver transplant is the most effective treatment for hepatocellular carcinoma (HCC) in cirrhosis. Due to organs shortage, the proper selection of patients is imperative. Prevailing clinical morphological models used in most centres (Milan Criteria), can exclude potential candidates and include patients with aggressive biological behaviour. To more accurately select candidates …

  • 14 Jun, 2022
68Ga-FAPI-04 PET/CT for the Detection of Oral Carcinoma

invasive range of the oral carcinoma, locate and qualitatively diagnose the tumor, and make early diagnosis and restaging of recurrent tumor.

  • 23 Aug, 2021
  • 1 location
Optimized Diffusion-Weighted Imaging for the Evaluation of Post-Treatment Squamous Cell Carcinoma in the Neck: Comparative Study With FDG PET/CT

imaging (DWI) pulse sequence to identify more accurately recurrent tumors as well as early non-responders to therapy.

chemotherapy regimen
squamous cell carcinoma
pet-ct scan
  • 15 Sep, 2021
  • 1 location