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Found 84 clinical trials
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Study of HB-200 alone and with pembrolizumab for patients with Recurrent/ Metastatic HPV 16+ Head and Neck and other Cancers

HB-201 and HB-202 are study drugs which are designed to train the body to recognize and fight substances found in HPV16+ cancer. This trial studies the safety and anti-cancer effect of HB-201 and HB-202 in people. HPV is a group of more than 200 related viruses, each given a number. HPV …

head and neck cancer
neck cancer
pembrolizumab
cancer
squamous cell carcinoma
  • 0 views
  • 27 May, 2022
  • 16 locations
Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers

The Radium Hospital Oslo University Hospital Estimated date of first patient enrolled: 3rd quarter 2021 Anticipated recruitment period: 4 years Estimated date of last patient completed: 4th quarter 2025 Locally advanced pelvic cancer that requires total pelvic exenteration Expected study-specific follow-up period per patient: 5 years according to standard follow-up …

  • 0 views
  • 23 Mar, 2022
68Ga-NODAGA-RGD PET/ CT for Tumoral Neoangiogenesis

) is indicated for initial extension evaluation or suspicion of recurrent tumor.

  • 0 views
  • 05 Jul, 2022
  • 1 location
Study of E7386 in Participants With Selected Advanced Neoplasms

This study will be conducted to assess the safety/tolerability profile of E7386 as a single agent administered orally in participants with selected advanced or recurrent neoplasms and to

  • 54 views
  • 29 Jan, 2022
  • 3 locations
Salvage Systemic Therapy With or Without Stereotactic Ablative Radiotherapy for Recurrent Ovarian Cancer (SABR-ROC)

therapy is often difficult because recurrent tumors do not respond uniformly to systemic therapy. In the 1980~1990s, whole abdomen irradiation had been tried and faded out owing to many side

  • 0 views
  • 25 Jul, 2022
  • 1 location
Study of the of the Safety and Tolerability of TT-00434 in Patients With Advanced Solid Tumors

This is a phase I study of the safety, tolerability, pharmacokinetics profile, and preliminary efficacy of TT-00434 in patients with advanced solid tumors.

  • 0 views
  • 02 Nov, 2021
  • 3 locations
GD2/CD56 Bi-specific CAR-T Cell Therapy

The purpose of this clinical trial is to assess the feasibility, safety and efficacy of anti-GD2/CD56 bi-specific CAR-T cell therapy in patients with GD2 and/or CD56 positive cancer. Another goal of the study is to learn more about the function of the anti-GD2/CD56 bi-specific CAR-T cells and their persistency in …

  • 0 views
  • 14 Jul, 2022
  • 1 location
First-in-human Phase I to Evaluate PEP-010 as Single Agent and in Combination With Paclitaxel (CleverPeptide)

This is an open-label, non-controlled, multicenter, dose escalation, first-in-human phase I clinical trial with an expansion phase designed to assess the safety, tolerability, PK and PD parameters, and preliminary antitumor activity of intravenous dosing of PEP-010 as single agent and in combination with paclitaxel. PEP-010 will be administered as single …

  • 0 views
  • 31 May, 2021
  • 3 locations
GD2/CD70 Bi-specific CAR-T Cell Therapy

The purpose of this study is to assess the feasibility, safety and efficacy of GD2/CD70 bi-specific CAR-T cell therapy in patients with GD2 and/or CD70 positive tumor. Another goal of the study is to learn more about the function of the GD2/CD70 bi-specific CAR-T cells and their persistency in patients.

  • 0 views
  • 10 Jul, 2022
  • 1 location
PSMA/CD70 Bi-specific CAR-T Cell Therapy

The purpose of this study is to assess the feasibility, safety and efficacy of anti-PSMA/CD70 bi-specific CAR-T cell therapy in patients with CD70 and PSMA positive malignancies. Another goal of the study is to learn more about the function of the PSMA/CD70 bi-specific CAR-T cells and their persistency in patients.

  • 0 views
  • 11 Jul, 2022
  • 1 location