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Found 414 clinical trials
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Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery

This is a single-center prospective clinical trial to evaluate non-inferiority of indocyanine green guided sentinel lymph node biopsy compared with the gold standard Technecium99 guided sentinel lymph node biopsy in patients with cancers and subjected to surgery. The diagnostic performance and the tolerance of indocyanine green (ICG) to the radio-isotope …

cancer surgery
cancer
sentinel node
indocyanine green
sentinel lymph node biopsy
  • 29 views
  • 03 Feb, 2021
  • 2 locations
None
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

larotrectinib
palbociclib
afatinib dimaleate
dasatinib
oophorectomy
  • 6118 views
  • 05 Dec, 2021
  • 1030 locations
None
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

measurable disease
gastric cancer
carcinoma
cancer of the ovary
lung carcinoma
  • 179 views
  • 08 Nov, 2021
  • 13 locations
None
A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer

This trial will look at a drug called SEA-TGT (also known as SGN-TGT) to find out whether it is safe for patients with solid tumors and lymphomas. It will study SEA-TGT to find out what its side effects are. A side effect is anything the drug does besides treating cancer. …

brentuximab vedotin
stage iv non-small cell lung cancer
progressive disease
measurable disease
carcinoma
  • 2 views
  • 29 Nov, 2021
  • 24 locations
None
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

ipilimumab
oophorectomy
carcinoma
immunosuppressive
cancer of the ovary
  • 6055 views
  • 05 Dec, 2021
  • 819 locations
None
Connecting Families to Overcome Ovarian Cancer

This study tests a multi-component, low cost, message-based communication outreach intervention to engage ovarian cancer survivors and their at-risk relatives in considering cancer genetic services. The intervention includes foot-in-the-door techniques, tailored/targeted print, website support, and short messages to expand reach of prevention messages.

BRCA1/2
fallopian tube
BRCA1
breast cancer
cancer of the ovary
  • 0 views
  • 30 Sep, 2021
  • 1 location
None
A Study of Tilvestamab (BGB149) in Relapsed Platinum-resistant High-grade Serous Ovarian Cancer (HGSOC) Participants

The primary purpose is to assess the safety and tolerability of tilvestamab following IV administration of multiple doses to participants with HGSOC who have been treated with at least 1 complete course of platinum-based chemotherapy and whose disease has relapsed with platinum resistance ([PRR]-HGSOC) and to determine the plasma pharmacokinetics …

cancer chemotherapy
platinum-based chemotherapy
cancer of the ovary
  • 0 views
  • 29 May, 2021
  • 9 locations
None
Carboplatin and Paclitaxel With or Without Cediranib in Treating Women With Relapsed Ovarian Epithelial Cancer Fallopian Tube Cancer or Primary Peritoneal Cancer

RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cediranib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth …

fallopian tube
peritoneal cancer
carboplatin
ovarian epithelial cancer
combination chemotherapy
  • 41 views
  • 07 Nov, 2020
  • 6 locations
None
Alpelisib Plus Olaparib in Platinum-resistant/Refractory High-grade Serous Ovarian Cancer With no Germline BRCA Mutation Detected

The objective of this study is to assess the efficacy and safety of the combination of alpelisib and olaparib compared with single agent cytotoxic chemotherapy in patients with platinum resistant or refractory high-grade serous ovarian cancer, with no germline BRCA mutation detected.

BRCA1/2
measurable disease
cancer chemotherapy
paclitaxel
cancer of the ovary
  • 0 views
  • 05 Dec, 2021
  • 8 locations
None
Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

stage III epithelial ovarian cancer randomizing between primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy

ovarian epithelial carcinoma
fallopian tube
intraperitoneal chemotherapy
cytoreductive surgery
cancer chemotherapy
  • 0 views
  • 08 Oct, 2021
  • 12 locations