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Found 414 clinical trials
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Deciphering Mechanisms Underlying Cancer Immunogenicity

This trial is a translational, open-label, monocentric, prospective cohort study of 900 patients aiming to describe the PD-1 (programmed death) expression in T cells (T lymphocytes) in different solid tumors. The study will be conducted on a population of patients with local and/or metastatic malignant solid tumor and who are …

ovarian cancer
lung cancer
cancer of the ovary
ascites
cin 3
  • 0 views
  • 26 Jan, 2021
  • 2 locations
None
Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial

The investigators hypothesize that an increase in dietary fiber intake during radiation therapy may provide better long-term intestinal health for the cancer survivor. If the hypothesis is not correct, the increased intake may only mean an increase in acute side effects. All participants are advised to consume at least 16 …

primary cancer
bladder tumor
  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Identifying and Caring for Individuals With Inherited Cancer Syndrome

This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and …

primary cancer
carcinoma
ductal carcinoma in situ
ductal carcinoma
BRCA2
  • 13 views
  • 06 Oct, 2021
  • 2 locations
None
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

carboplatin
parp inhibitor
antineoplastic
paclitaxel
  • 3 views
  • 04 Sep, 2021
  • 30 locations
None
Prospective Biobanking Study in Ovarian Breast and Head and Neck Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself Its Microenvironment and Immune Response (SCANDARE)

SCANDARE is a prospective biobanking study on tumor (+/- nodes), plasma and blood samples at different time points in ovarian, triple negative breast and head and neck cancer patients. This study will allowed to identify new molecular and/or immunological biomarkers associated with clinical and biological features of the tumors. All …

cancer chemotherapy
cancer of the ovary
cancer
triple-negative breast cancer
ovarian cancer
  • 3 views
  • 28 Jan, 2021
  • 2 locations
None
A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.

The purpose of this study is to assess the safety, tolerability, and preliminary anti-tumor activity of experimental medication NZV930 alone and when combined with PDR001 and/or NIR178, in patients with advanced cancers

  • 507 views
  • 30 Nov, 2021
  • 12 locations
None
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health

This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial, renal, thyroid, and ovarian cancers, as well as multiple myeloma and non-Hodgkin Lymphoma. Overarching outcomes also include physical function and performance, …

multiple myeloma
cancer chemotherapy
carcinoma
ductal carcinoma in situ
ductal carcinoma
  • 42 views
  • 05 Nov, 2021
  • 2 locations
None
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

This is a phase I/II, non randomized, open-label, dose escalation study to investigate the safety, tolerability and preliminary efficacy of CB-103.

cancer chemotherapy
aptt
mantle cell lymphoma
t-cell lymphoma
metastatic disease
  • 281 views
  • 26 Jan, 2021
  • 12 locations
None
A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors

This research study is done to test how well different types of cancer respond to the drug called larotrectinib. The cancer must have a change in a particular gene (NTRK1, NTRK2 or NTRK3). Larotrectinib is a drug that blocks the actions of these NTRK genes in cancer cells and can …

NTRK
tyrosine
cancer
lung carcinoma
breast cancer
  • 15 views
  • 02 Nov, 2021
  • 205 locations
None
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Solid Tumors Malignancies

This clinical trial is evaluating a drug called BT8009 alone and in combination with nivolumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The main goals of this study are to: Find the recommended dose of BT8009 …

carcinoma
mammogram
triple negative breast cancer
targeted therapy
breast cancer
  • 99 views
  • 05 Dec, 2021
  • 16 locations