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Found 416 clinical trials
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An Audit of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Peritoneal carcinomatosis is a common event in the natural history of colorectal and other digestive tract cancers. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provides a promising therapeutic option for highly selected patients with peritoneal carcinomatosis arising from different malignancies such as colorectal cancer, gastric cancer, ovarian cancer, or …

intraperitoneal chemotherapy
metastasis
cytoreductive surgery
cancer of the ovary
cancer chemotherapy
  • 19 views
  • 10 Oct, 2021
  • 1 location
None
Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy

The purpose of this study is evaluate whether a prehabilitation program is feasible and useful for women with advanced ovarian cancer receiving chemotherapy in preparation for debulking surgery.

ovarian epithelial carcinoma
ovarian cancer
peritoneal carcinoma
cancer chemotherapy
cancer
  • 0 views
  • 19 Mar, 2021
  • 1 location
None
Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their Relatives

This trial collects information about factors that affect communication of genetic test results, decision-making, and access to genetic testing in women with hereditary gynecological cancers. Studying individuals who are positive for a genetic mutation and immediate biological family members (including a parent, full-sibling, or child) may help identify cancer genes …

breast cancer
palb2
BRCA2
MLH1
LKB1
  • 46 views
  • 24 Jan, 2021
  • 2 locations
None
Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal Cancers

Patients with primary peritoneal cancer or secondary peritoneal cancers from stomach, colorectal, appendiceal, and gynecological primary origin will be screened by pathology and staging to see if they are eligible to undergo cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC). To be eligible for the study, patients must be over …

antineoplastic
antineoplastic agents
peritoneal cancer
mitomycin
cancer chemotherapy
  • 19 views
  • 31 Aug, 2021
  • 1 location
None
Developing a Test for the Detection of Ovarian Cancer

The study aims to develop a test for early detection of ovarian cancer using DNA from a growth involving the ovary found in a washing of the uterus (womb), and proteins found in the blood. The samples of the wash and the blood will be taken before surgery. After surgery, …

  • 0 views
  • 24 Mar, 2021
  • 6 locations
None
Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

The goals of this prospective, observational cohort study are to determine the feasibility of implementing paclitaxel therapeutic drug monitoring for cancer patients and explore the relationship between paclitaxel drug exposure and the development of neuropathic symptoms. This trial studies if paclitaxel can be consistently measured in the blood of patients …

topotecan
breast cancer
therapeutic drug monitoring
cyclophosphamide
trastuzumab
  • 0 views
  • 29 Nov, 2021
  • 1 location
None
Thymidine Kinase 1 in Risk Assessment for Hereditary Breast /Ovarian Cancer

This study aimed to compare the activity of Thymidine Kinase 1 in serum of two groups of woman at high and normal risk for breast/ovary cancer.

breast cancer
combinations
cancer of the ovary
  • 8 views
  • 07 Nov, 2020
  • 1 location
None
Liquid Biopsies for Improving the Pre-operative Diagnosis of Ovarian Cancer

An accurate preoperative diagnosis of an ovarian tumor is important for the patients' surgical work-up, proper referral to oncological centers and for the patients' mental wellbeing since uncertainty about the nature (benign vs malignant) of an ovarian tumor may cause anxiety. Currently, the Risk of Malignancy Index (RMI), with a …

cancer of the ovary
cancer antigen 125
tumor cells
  • 0 views
  • 31 Jul, 2021
  • 4 locations
None
Spectroscopy in Ovarian Cancer

Ovarian cancer is the eighth most common cause of cancer death in the world. Advanced stage at diagnosis is associated with lower survival rates, thus early detection appears to have an important role. Raman Spectroscopy is a non-invasive technique that uses the interaction of light to identify the composition of …

cancer chemotherapy
cancer of the ovary
  • 0 views
  • 22 Jul, 2021
  • 1 location
None
The Effect of Glucose Level and Diabetes Mellitus on Ctrough of Olaparib

Monitored therapy of olaparib concentrations in the blood of diabetic population probably will assess the need for individual dosing of the drug. The project concerns on the monitored therapy of olaparib in a population of patients with DM, hyperglycemia and normal glucose level. Currently, there are no studies assessing the …

olaparib
cancer of the ovary
  • 0 views
  • 28 Oct, 2021
  • 1 location