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Found 71 clinical trials
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LITT Followed by Hypofractionated RT for Recurrent Gliomas

The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with recurrent gliomas

karnofsky performance status
recurrent tumor
MRI
treatment regimen
brain mri
  • 2 views
  • 02 Aug, 2021
  • 4 locations
None
Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

estimate the effect size of such combinational treatment approach in recurrent high-grade glioma with DNA damage repair deficiency (dDDR)

  • 0 views
  • 25 Aug, 2021
  • 1 location
None
Treatment With Azacitidine of Recurrent Gliomas With IDH1/2 Mutation

Glioma are the most commun frequent brain tumour. Mutation of Isocitrate DeHydrogenase IDH1 or IDH2 genes affect 40% of gliomas, mostly grade II and III gliomas. Despite IDH mutated gliomas (IDHm glioma) have a better prognosis compared to the IDH wild type counterparts, they invariably recur after standard treatment with …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Neoadjuvant Carilizumab and Apatinib for Recurrent High-Grade Glioma

glioma patients is still very poor. The study aim to Evaluate the Safety and efficiency of Using the neoadjuvant therapy with Carilizumab and Apatinib in patients with Recurrent High-Grade Glioma.

  • 0 views
  • 25 Jan, 2021
  • 1 location
None
D2C7 for Adult Patients With Recurrent Malignant Glioma

recurrent malignant glioma (diagnosis results are typically received within 24-48 hours following biopsy), the investigators will proceed with the D2C7-IT infusion. If no tumor is identified, the catheters

aptt
malignant glioma
recurrent tumor
brain mri
neutrophil count
  • 136 views
  • 22 Sep, 2021
  • 1 location
None
Personalized Vaccine for Patients With Recurrent Malignant Glioma

malignant glioma.

recurrent malignant glioma
malignant glioma
measurable disease
  • 0 views
  • 05 Jul, 2021
  • 1 location
None
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

This clinical trial constructs and tests a novel multinuclear metabolic magnetic resonance imaging (MRI) sequence in patients with glioma (brain tumor) that is newly diagnosed or has come back (recurrent). This trial aims to develop new diagnostic imaging technology that may bridge gaps between early detection and diagnosis, prognosis, and …

recurrent glioma
cancer
Accepts healthy volunteers
brain tumor
MRI
  • 0 views
  • 07 Oct, 2021
  • 1 location
None
A Phase I/IIa Study of Cerebraca Wafer Plus Adjuvant Temozolomide (TMZ) in Patients With Recurrent High Grade Glioma

High Grade Glioma. High grade gliomas, glioblastoma multiforme (grade IV) and anaplastic anaplastic astrocytoma (Grade III), are the most comment malignant brain tumor. The cause of gliomas

  • 0 views
  • 06 Apr, 2021
  • 3 locations
None
A Study of Anlotinib in the Treatment of Recurrent High-grade Glioma

This is a phase II, open-label, single center study, aiming to investigate safety and efficacy of anlotinib in treatment of recurrent high-grade glioma.

  • 0 views
  • 08 Apr, 2021
  • 1 location
None
Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype

The purpose of this study is to test if the study drug called pembrolizumab could control the growth or shrink the cancer but it could also cause side effects. Researchers hope to learn if the study drug will shrink the cancer by half, or prevent it from growing for at …

malignant glioma
recurrent tumor
cancer
neutrophil count
astrocytoma
  • 0 views
  • 01 Oct, 2021
  • 16 locations