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Found 107 clinical trials
Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM

The purpose of this study is to evaluate the safety and feasibility of the Exablate Model 4000 Type 2 system when used as a tool to open the blood-brain-barrier (BBB) in subjects with recurrent

glioblastoma multiforme
tumor progression
  • 14 views
  • 15 Dec, 2021
  • 4 locations
Feasibility of Individualized Therapy for Recurrent GBM

The current study will test the ability and likelihood of successfully implementing individualized combination treatment recommendations for adult patients with surgically-resectable recurrent

cancer
glioblastoma multiforme
gliosarcoma
neutrophil count
  • 13 views
  • 01 Feb, 2022
  • 1 location
Individualized Systems Medicine Functional Profiling for Recurrent Glioblastoma

A study to determine the feasibility and safety of individualized cancer stem cell targeted therapy based on high-throughput functional profiling of FDA/EMA-approved drugs in patients with GBM that has recurred or progressed following standards-of-care (RT, TMZ).

  • 0 views
  • 20 Sep, 2021
  • 1 location
Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

dose level for further clinical development of fb-PMT to treat recurrent Glioblastoma.

cancer
brain tumor
recurrent glioblastoma
karnofsky performance status
  • 0 views
  • 24 May, 2022
  • 1 location
Irinotecan And Bevacizumab Combined With Re-radiotherapy in Recurrent Glioblastoma

This is a phase I study to observe the safety and efficacy of irinotecan and bevacizumab combined with re-radiotherapy in the treatment of recurrent glioblastoma. The study will provide a higher

  • 0 views
  • 25 Mar, 2022
  • 1 location
GX-I7 in Combination With Bevacizumab in Recurrent Glioblastoma (GBM) Patients

The purpose of this study is to evaluate the efficacy and safety of GX-I7 in combination with bevacizumab in subjects with recurrent glioblastoma.

  • 0 views
  • 27 Jul, 2022
  • 1 location
Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG)

The study will investigate combined stereotactic radiosurgery and enhanced immunotherapy for recurrent glioblastomas. Immune adjuvants will be injected intratumorally and systemically to induce

  • 0 views
  • 29 Nov, 2021
  • 1 location
Combined Treatment of Camrelizumab and Bevacizumab for Adult Patients With Recurrent Glioblastoma (GBM)

This study is intend to explore the efficacy and safety of combined treatment of camrelizumab and bevacizumab in adult patients with recurrent glioblastoma.

  • 0 views
  • 17 Jul, 2021
  • 1 location
Personalized Functional Profiling in Metastatic Gastrointestinal Cancer or Recurrent Glioblastoma Patients in Luxembourg.

The investigators are developing a novel standardized and centralized approach named Integrated Personalized Functional Profiling (PFP) in Luxembourg. Based on recent improvements in cancer biopsy-derived 3D-culture technologies the PFP process will screen patient derived cells (PDCs) with FDA/EMA-approved drugs to generate personalized functional response profiles. The selected drug through PFP …

glioblastoma multiforme
cancer treatment
  • 4 views
  • 16 Mar, 2022
  • 2 locations
Neoadjuvant PD-1 Antibody Alone or Combined With DC Vaccines for Recurrent Glioblastoma

Glioblastoma multiforme (GBM) are the most prevalent malignant tumor in central nervous system. At recurrence, no clear standard-of-care therapy is agreed for recurrent GBM (rGBM) and median

  • 0 views
  • 08 Dec, 2021
  • 1 location