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Found 89 clinical trials
Proof -of -Concept Study To Stratify Targeted Therapies Adapted To Molecular Profiling

including pediatric patients, performing an on-purpose intervention and molecular profiling in recurrent tumors. Together with more than 500 adult patients, between December 2012 to August 2014, the tumors

  • 39 views
  • 23 Jan, 2021
  • 5 locations
I-125 Versus Pd-103 for Medium Risk Prostate Cancer

hypothesis: the shorter half-life of Pd-103 versus I-125, will increase the rate of tumor eradication. A total of 660 patients with AJC clinical stage T1c-T2a prostatic carcinoma (Gleason grade 7 to 9 and/or PSA 10–20 ng/ml) will be randomized to implantation with I-125 (144 Gy) versus Pd-103 (124 Gy).

prostate carcinoma
carcinoma
  • 16 views
  • 07 Nov, 2020
  • 1 location
68Ga-NODAGA-RGD PET/ CT for Tumoral Neoangiogenesis

) is indicated for initial extension evaluation or suspicion of recurrent tumor.

  • 0 views
  • 05 Aug, 2021
  • 1 location
Study of E7386 in Subjects With Selected Advanced Neoplasms

This study will be conducted to assess the safety/tolerability profile of E7386 as a single agent administered orally in participants with selected advanced or recurrent neoplasms and to

  • 54 views
  • 26 Jan, 2021
  • 3 locations
Study of the of the Safety and Tolerability of TT-00434 in Patients With Advanced Solid Tumors

This is a phase I study of the safety, tolerability, pharmacokinetics profile, and preliminary efficacy of TT-00434 in patients with advanced solid tumors.

  • 0 views
  • 13 Jun, 2021
  • 3 locations
Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle

RATIONALE: Imaging procedures, such as MRI and CT scan, may find recurrent cancer. It is not yet known which MRI or CT scan schedule is more effective in finding recurrent cancer

seminoma
cancer
ct scan
  • 717 views
  • 07 Nov, 2020
  • 12 locations
First-in-human Phase I to Evaluate PEP-010 as Single Agent and in Combination With Paclitaxel (CleverPeptide)

This is an open-label, non-controlled, multicenter, dose escalation, first-in-human phase I clinical trial with an expansion phase designed to assess the safety, tolerability, PK and PD parameters, and preliminary antitumor activity of intravenous dosing of PEP-010 as single agent and in combination with paclitaxel. PEP-010 will be administered as single …

  • 0 views
  • 31 May, 2021
  • 3 locations
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer.

cancer surgery
rectal carcinoma
metastasis
  • 2 views
  • 26 Jan, 2021
  • 9 locations
European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors

pediatric recurrent cancers. Increasingly, stratified approaches are being implemented to enrich clinical trials of molecularly targeted agents and possibly improve outcomes in specific populations i.e. a

  • 38 views
  • 06 Mar, 2021
  • 8 locations
A Study of V937 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (V937-013)

The purpose of this study is to evaluate the safety, tolerability, and efficacy in participants with advanced/metastatic or recurrent malignancies who receive V937 in Combination with

trastuzumab
triple-negative breast cancer
solid tumor
metastasis
HER2
  • 0 views
  • 18 Sep, 2021
  • 26 locations