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Found 887 clinical trials
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ROLARR: RObotic versus LAparoscopic Resection for Rectal cancer. An international multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer.

ROLARR: RObotic versus LAparoscopic Resection for Rectal cancer. An international multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard

  • 98 views
  • 23 Nov, 2020
  • 1 location
featured
A Randomized Phase 3 Study of MRTX849 in Combination with Cetuximab Versus Chemotherapy in Patients with Advanced Colorectal Cancer with KRAS G12C Mutation with Disease Progression On or After Standard First-Line Therapy (KRYSTAL-10)

Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus chemotherapy in the second-line treatment setting in patients with CRC with KRAS G12C mutation.

  • 5 views
  • 13 Sep, 2021
  • 42 locations
featured
Z6051 - A Phase III Prospective Randomized Trial Comparing Laparoscopic-assisted Resection Versus Open Resection for Rectal Cancer

Z6051 - A Phase III Prospective Randomized Trial Comparing Laparoscopic-assisted Resection Versus Open Resection for Rectal Cancer

  • 74 views
  • 25 Mar, 2021
  • 1 location
featured
What if there were a simpler way to find colorectal cancer?

ECLIPSE is being done to find out if a simple blood test can find early signs of colorectal cancer. Colorectal cancer is the #2 cause of death among adults with cancer, but it doesn’t have to be.  If found early, it’s one of the most preventable and treatable cancers.  NOW …

  • 13 views
  • 23 Nov, 2020
  • 1 location
Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer

advanced rectal cancer. The hypothesis is 3-year disease-free survival in TNT group was non-inferior to that in CRT group.

chemoradiotherapy
adenocarcinoma of rectum
pelvic mri
adenocarcinoma
  • 0 views
  • 21 Jul, 2021
  • 1 location
The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer

The addition of Oxaliplatin to conventionally fractionated chemoradiation (FULV or capecitabine) is considered as standard in unresectable rectal cancer by the panel of experts. The

chemoradiotherapy
capecitabine
metastasis
oxaliplatin
  • 1 views
  • 07 Nov, 2020
  • 1 location
A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradiation Therapy (CCRT)

This is a three-year research project. The major aims of this study are to:(1) compare the functional recovery and oncologic results in patients with advance rectal cancer treated by

adenocarcinoma
open surgery
concurrent chemoradiation
chemoradiotherapy
adenocarcinoma of rectum
  • 0 views
  • 07 Nov, 2020
Comparison of Two Types of Surgery in Treating Patients With Rectal Cancer

RATIONALE: Surgery to remove the tumor may be an effective treatment for rectal cancer. It is not yet known whether one type of surgery is more effective than another for rectal cancer

conventional surgery
rectal carcinoma
  • 21 views
  • 07 Nov, 2020
  • 2 locations
Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation

The CIRCULATE study evaluates the adjuvant therapy in patients with colon cancer UICC stage II. The primary aim of the study is to compare the disease free survival in patients who are positive for postoperative circulating tumour DNA with vs. without capecitabine.

  • 0 views
  • 24 Jan, 2021