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Found 33 clinical trials
Fixed-Dose Trial in Early Parkinson's Disease (TemPo-1)

The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease.

dopa
dementia
early parkinson's
essential tremor
bradykinesia
  • 86 views
  • 21 Sep, 2022
  • 50 locations
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study (study number PD0053) is a clinical research study for people with early-stage Parkinson’s disease (<2 years). The aim of the study is to find out whether an investigational medication known as UCB0599 can slow the progression of Parkinson’s disease and whether it is efficacious and well tolerated (which means …

motor symptoms
resting tremor
bradykinesia
tremor
hoehn and yahr scale
  • 327 views
  • 19 Sep, 2022
  • 65 locations
Neurofunctional Correlates of the Behavioral Modifications Associated With Tachidino in Children With Developmental Dyslexia (TACHIDINO)

Developmental dyslexia (DD) is the most common learning disorder. Multiple cognitive and sensory domains contribute to the etiology of DD and develop before reading acquisition. Atypical brain

developmental dyslexia
learning disorder
  • 7 views
  • 07 Jun, 2022
  • 1 location
Behavioural and Physiological Measures of Young Students With Dyslexia

The proposed is reading intervention study to track neural changes in the brain. Students with dyslexia will participate in a reading study. Pre and post-analysis data will be obtained to see

Accepts healthy volunteers
  • 0 views
  • 26 May, 2022
  • 1 location
Randomized Trial in Advanced Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.

Phase II study in patient with advanced Soft Tissue Sarcoma (STS) patients who have already received or are not suitable, for a doxorubicin-based treatment.

  • 0 views
  • 07 Nov, 2021
  • 15 locations
Treatment for Elderly Fit Newly Diagnosed Multiple Myeloma Patients Aged Between 65 and 80 Years

The study is designed as a randomized, controlled, open-label, assessor blind, multicenter superiority trial with three parallel groups, and primary endpoint of immunophenotypic complete responses at 18 months after randomization. Block randomization will be performed with a 1:1:1 allocation ratio. Patients will be randomized up front to 3 arms. Patients …

  • 13 views
  • 24 Mar, 2021
  • 89 locations
Development of an Arabic Central Auditory Processing Remediation Program for Dyslexic Children With(C)APD

Rehabilitation of dyslexic children with (cental) auditory processing disorder. The first group will receive the proposed program the arabic version of differential processing training

  • 1 views
  • 31 Jan, 2021
  • 1 location
Executive Function in Early Childhood

Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via executive functions (EF), have not been unpacked. This project will use a longitudinal …

Accepts healthy volunteers
  • 8 views
  • 22 Jul, 2022
  • 1 location
Neurocognitive Factors in EdTech Intervention Response

The current project will carry out a large-scale, randomized controlled trial (RCT) to examine the effectiveness of a home-administered technology-based treatment for reading disability

learning disorder
cognitive assessment
Accepts healthy volunteers
electroencephalogram
  • 28 views
  • 30 Jun, 2022
  • 1 location
Interventions for Reading Disabilities in NF1

-based reading tutoring originally developed to treat reading disability in the general population. Combining our work with that by other researchers suggesting that a medication (Lovastatin) may

psychiatric disorder
kidney failure
genetic disorder
brain tumors
deficit
  • 169 views
  • 09 Jul, 2022
  • 1 location