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Found 15 clinical trials
A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis

The purpose of this study is to determine whether oral temanogrel improves digital blood flow in participants with Raynaud's phenomenon secondary to systemic sclerosis (SSc-RP) as a potential

  • 0 views
  • 25 Apr, 2022
  • 6 locations
A Study to Investigate Safety of GS-248 and Efficacy on Raynauds' Phenomenon in Systemic Sclerosis

The primary objective of this study is to determine the safety, and evaluate the efficacy of GS-248 versus placebo on Raynaud's Phenomenon (RP) in subjects with Systemic Sclerosis (SSc).

rheumatism
raynaud's phenomenon
myositis
calcium channel blockers
calcium
  • 0 views
  • 22 Mar, 2022
  • 12 locations
Botulinum Toxin in Raynaud's Phenomenon

Raynaud's Phenomenon (RP) is the most common vasospastic disorder encountered by hand surgeons with an estimated prevalence of 5% in the general population. It's manifestations are broad, and

raynaud's phenomenon
medical therapies
botulinum toxin
  • 0 views
  • 22 Mar, 2022
  • 1 location
Nutritional Strategies to Increase Nitric Oxide Signaling in Raynaud's Phenomenon

phenomenon severity. Raynaud's phenomenon severity will be assessed through the Raynaud Condition Score, daily frequency of attacks or cumulative attack duration (expressed as min) daily collected by

nitric oxide
beetroot juice
citrulline
raynaud's phenomenon
scleroderma
  • 36 views
  • 23 May, 2021
  • 1 location
Rheopheresis for Raynaud's and Digital Ulcers in Systemic Sclerosis (RHEACT)

In this feasibility study, we aim to explore therapeutic Rheopheresis (RheoP) as a novel treatment option for SSc-associated Raynaud's phenomenon and/or digital ulcers and compare it to the

raynaud's phenomenon
systemic sclerosis
raynaud's syndrome
ulceration
  • 0 views
  • 07 Apr, 2022
Apollo Device for Fatigue in Systemic Sclerosis

The purpose of this study is to learn about the effect of Apollo (a vibrating wearable about the side of an Apple Watch) on fatigue, Raynaud symptoms, depression, quality of life, and disease

systemic sclerosis
rheumatism
vasodilator
depression
raynaud's syndrome
  • 0 views
  • 16 Oct, 2021
  • 1 location
Exercise in People With Systemic Sclerosis (SScPF)

Raynaud's phenomenon and digital ulceration are two of the most common disease manifestations leading to digital and/or toe pain in systemic sclerosis (SSc). In addition to pain, fatigue has

raynaud's phenomenon
raynaud's syndrome
  • 0 views
  • 25 Mar, 2022
  • 1 location
Effectiveness of the EmoLED Medical Device in the Healing of Digital Ulcers in Patients With Scleroderma. (SUITABLE)

The present clinical study aims to compare, in the two groups of patients with acral ulcers, the reparative process of the injured area, the evaluation of the healing time (with "healing" interpreted as the complete re-epithelization of the wound) and the perception of pain through NRS scale.

  • 0 views
  • 11 May, 2022
Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre

Systemic sclerosis (SSc) is a rare form of connective tissue disease characterized by vascular involvement and the intensity of fibrosis. The lack of available treatment is largely due to the very fragmented understanding of the pathophysiology of SSc. However, one of the keys to conducting quality research on this disease …

progressive systemic sclerosis
rheumatism
raynaud's phenomenon
scleroderma
raynaud's syndrome
  • 0 views
  • 16 May, 2021
  • 1 location
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will …

sotalol
antiarrhythmic drug
fibrillation
flecainide
  • 313 views
  • 03 Mar, 2022
  • 1 location