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Found 17 clinical trials
Rapid Diagnosis of Pulmonary Tuberculosis

The purpose of this study is to test whether a saline nebulization (breathing in a mist of moist air through a mask) will help an individual cough up a better sputum sample to test for tuberculosis (TB). In addition, this study will test whether samples obtained with saline nebulization are …

HIV Infection
pulmonary tuberculosis
rapid diagnosis
  • 07 Nov, 2020
  • 1 location
Paediatric Rapid Sepsis Trigger (PRST) Tool

that will reduce the time to diagnosis and prompt the timely initiation of life-saving treatment. The key innovations are 1) a data-driven approach to rapid diagnosis of sepsis severity and 2) a low

  • 27 Jan, 2021
  • 2 locations
Improving TB Diagnosis and Treatment Through Basic Applied and Health Systems Research

TB is a global health problem and in South Africa rates as the second most important problem in terms of Burden of Disease. There are many reasons for this, among which are diagnostic difficulties, extended treatments, drug resistance and health care provision. This application is concerned with all these drivers …

  • 28 Feb, 2021
  • 2 locations
Study of Electrophysiological Markers Related to the Cognitive and Affective Processes Behind Empathic Behaviour in Schizophrenic Spectrum Disorder

developmental vulnerability for schizophrenia and identifying objective markers of this vulnerability could allow, in case of development of the pathology, a more rapid diagnosis and a more effective management

schizoaffective disorder
  • 25 Jan, 2021
  • 1 location
Preeclampsia Research on Vitamin D Inflammation & Depression

This study is designed to comprehensively investigate the anti-inflammatory role of vitamin D in reproductive aged women, and its association with preeclampsia and depression. Findings will have substantial impact providing new information implicated in the development of preeclampsia (a condition that may include hypertension, tissue swelling caused by excessive fluid, …

  • 03 Feb, 2021
  • 1 location
Impact of Rapid Screening for COVID-19 in Delocalized Biology in the Emergency Department

Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, first appeared in China, and then spread around the world. In December 2019, a group of patients with pneumonia of unknown origin were infected after exposure to the market in Wuhan, Hubei province, China. Very quickly, a new coronavirus was isolated from a …

  • 24 Mar, 2021
  • 1 location
Change of Neutrophil Gelatinase-Associated Lipocalin(NGAL) Following Sodium Phosphate Bowel Preparation(Pilot Study)

important to detect or prevent vulnerable patients. We would seek a sensitive and rapid diagnosis method of acute kidney injury following sodium phosphate bowel preparation. Within a few hours

renal injury
chronic kidney disease
renal ischemia
renal failure
  • 07 Nov, 2020
  • 1 location
Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis

The rapid diagnosis of tuberculosis (TB) in children remains a serious challenge owing to limitations in the existing diagnostic tests. TB meningitis (TBM), an extrapulmonary form of TB, is the

  • 27 Jan, 2021
  • 1 location
PCR Based Detection of Azole Resistance in A. Fumigatus to Improve Patient Outcome.

A standard treatment protocol for invasive aspergillosis (IA) will be implemented in several academic hematology centers in the Netherlands in which a diagnostic test demonstrating azole resistance by multiplex real-time polymerase chain reaction will guide the choice of appropriate antifungal treatment. Objectives Improve the outcome of patients infected with azole …

  • 23 Jan, 2021
  • 8 locations
Feasibility Study of Intermediate Doses of ARA-C With Autologous SCT as Consolidation of Low/Intermediate-risk AML

Create a network of institutions in developing countries that will perform AML diagnosis, risk classification, treatment, supportive care and follow-up evaluation according to a common protocol and will register data using common clinical research forms (CRFs) in a single database and available on the internet.

myelodysplastic syndromes
ejection fraction
acute promyelocytic leukemia
  • 21 Jan, 2021
  • 8 locations