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Found 21 clinical trials
OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD)

A 2-year, phase 3, multicentre, randomised, parallel-group, sham-controlled, double-masked study. Primary efficacy will be determined at Week 52.

  • 0 views
  • 09 Apr, 2021
  • 2 locations
Combination of Ranibizumab and Targeted Laser Photocoagulation

Intravitreal injections of Ranibizumab will be applied in all patients according to treatment guidelines. The experimental group will receive additional targeted laser photocoagulation of the

  • 0 views
  • 25 Jan, 2021
  • 8 locations
Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DME

The objective of this study is to evaluate if combination of intravitreal ranibizumab with micropulse laser shows non inferiority compared to intravitreal ranibizumab only in diabetic macular

ranibizumab
glycosylated hemoglobin
vegf
bevacizumab
photocoagulation
  • 1 views
  • 23 Jan, 2021
  • 1 location
25-G Vitrectomy With Ranibizumab or Triamcinolone Acetonide on PDR in China-Randomized Clinical Trial

Proliferative diabetic retinopathy(PDR) is the leading cause of visual loss in diabetic patients. Operation is an efficient method to treat PDR. Anti-vascular endothelial growth factor (anti-VEGF) can be used as an adjuvant therapy which can make operation more easy.

ranibizumab
vegf
visual loss
bevacizumab
vitrectomy
  • 5 views
  • 22 Jan, 2021
  • 1 location
Eylea and Lucentis for Macular Edema in Branch Retinal Vein Occlusion

Comparing time to recurrence of macular edema after an initial loading dose of at least three monthly anti VEGF injections (aflibercept or ranibizumab) for macular edema in BRVO.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Comparative Multicenter Randomized Study of Aflibercept Versus Placebo in Macular Telangiectasia Type 1

(ranibizumab and bevacizumab) showed mitigated results. More recently, authors have reported some favorable results with aflibercept in patients refractory to other anti-VEGF agents. Indeed a recent study

  • 0 views
  • 29 Jan, 2021
  • 1 location
Changes in Inflammatory Biomarkers Including Soluble CD14 and Hyperreflective Foci in DME Patients Treated With Aflibercept (FORESIGHT)

This study evaluates the effect of aflibercept on the change of cytokines incluing sCD14, MCP-1, IL-6, and ICAM-1 in the aqueous humor of DME patients. Additionally, changes of visual acuity (ETDRS), optical coherence tomography parameters including hyperreflective foci and thickness of macula are also investigated.

diabetes
aflibercept
optical coherence tomography
aflibercept injection
cytokines
  • 0 views
  • 25 Jan, 2021
  • 1 location
Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment

In this study, we aim to evaluate the efficacy and safety of an individualized dosing schedule comprising Aflibercept and RF-PDT in patients with polypoidal choroidal vasculopathy (PCV). The objective is to compare the visual improvement from baseline to month 12, in eyes with PCV treated with Aflibercept monotherapy versus combination …

  • 0 views
  • 25 Mar, 2021
  • 3 locations
A Comparison of Standard Laser With Micropulse Laser for the Treatment of Diabetic Macular Oedema.

DIAMONDS is a Randomised Controlled Clinical Trial that is being carried out in the UK to determine the clinical effectiveness and cost-effectiveness of micropulse laser, compared with standard laser, for the treatment of diabetic macular oedema.

spectral domain optical coherence tomography
diabetic retinopathy
optical coherence tomography
retinopathy
  • 66 views
  • 22 Jan, 2021
  • 12 locations
Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial

The Macular Edema Ranibizumab v. Intravitreal anti-inflammatory Therapy (MERIT) Trial will compare the relative efficacy and safety of intravitreal methotrexate, intravitreal ranibizumab, and

triamcinolone
angiography
methotrexate
cysts
macular edema
  • 324 views
  • 25 Jan, 2021
  • 31 locations