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Found 321 clinical trials
Virtual Reality MObility for Burn Patients (VR-MOBILE)

Background In the acute phase, burn patients undergo several painful procedures. Pediatric burn care procedures conducted in hydrotherapy have been known to generate severe pain intensity and moderate to high levels of anxiety. Hydrotherapy treatments are done with the use of opioids and benzodiazepines for pain and anxiety. Unfortunately, non-pharmacological …

  • 04 Oct, 2022
  • 1 location
Does ESWT With BoNTA Treatment Improve Outcomes When Compared to Standard Management for Upper Limb Spasticity Patient.

Background Effective management of spasticity, a debilitating and challenging condition afflicting many recovering from and living with neurological conditions, may reduce long term consequences such as limb contracture, skin breakdown, compromised mobility, caregiver burden and discomfort. In rehabilitation, spasticity represents a significant barrier to successful rehabilitation outcomes. Effective spasticity management …

  • 04 Oct, 2022
  • 1 location
Fixed Versus Adjustable Loop in ACL Reconstruction

Study Aims and Objectives: To investigate the following null hypothesis: that there is no difference in clinical and functional outcome when comparing outcomes of Anterior Cruciate Ligament (ACL) reconstruction when comparing femoral side graft fixation with either a fixed versus an adjustable suspensory loop system. The research team will achieve …

knee joint laxity
anterior cruciate ligament injury
meniscal tear
  • 29 Jan, 2022
  • 1 location
Fractional CO2 Laser Treatment of Hypertrophic Scars

Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints. There are also often significant psychosocial elements with these scars that are especially significant in the vulnerable pediatric population and their parents. Current scar treatment modalities are limited. …

Accepts healthy volunteers
  • 17 Oct, 2021
  • 1 location
Traditional Versus Alternative Alignment in TKR

As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients satisfied with their operation. Recently, attention has focussed on alignment of …

Accepts healthy volunteers
  • 30 May, 2022
  • 1 location
PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2 (PERK2)

lactose placebo twice daily orally for 6 weeks) and a primary endpoint of elbow extension-flexion range of motion (ROM) arc at 12 weeks post-randomization.

  • 16 Oct, 2022
  • 15 locations
Robotic Lobectomy vs. Thoracoscopic Lobectomy for Early Stage Lung Cancer: RCT

lung using 3-dimensional imaging. The instruments give the surgeons increased range of motion during the surgery, and research demonstrates that RTS has a less steep learning curve as compared to VATS

thoracoscopic surgery
pulmonary resection
lung cancer
  • 24 Feb, 2022
  • 1 location
STaR (Surgical Timing and Rehabilitation) Trial for Multiple Ligament Knee Injuries

The purpose of this study is to investigate effects of timing of surgery (early vs. delayed) and timing of post-operative rehabilitation (early vs. delayed) for the treatment of military personnel and civilians that sustain a multiple ligament knee injury. To achieve this overall objective of this project, we will conduct …

  • 15 Oct, 2022
  • 1 location
Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery

Cryotherapy has been used to enhance recovery after orthopaedic surgery. Many devices are available but few can guarantee a temperature regulation during a prolonged time and therefore have been criticized. The arrival of new advanced cryotherapy devices made it possible to test the effect of prolonged cooling on rehabilitation after …

  • 26 Apr, 2022
  • 1 location
Anterior Cruciate Ligament Reconstruction Using Bone Patellar Bone or Quad Tendon Autograft With or Without Lateral Extra-Articular Tenodesis in Individuals Who Are at High Risk of Graft Failure (STABILITY 2) (STABILITY 2)

Anterior cruciate ligament (ACL) rupture is one of the most common musculoskeletal injuries in young individuals, particularly those that are active in sports. Up to 30% of individuals under the age of 20 years suffer a re-injury to the reconstructed ACL. Revision ACLR has been associated with degeneration of the …

joint laxity
ligament reconstruction
  • 14 Oct, 2022
  • 17 locations