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Found 32 clinical trials
Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast

Following breast-conserving surgery (BCS) for localized ductal carcinoma in situ (DCIS) of the breast, whole-breast irradiation (WBRT) is a standard of care, reducing the absolute rate of in-breast recurrences (IBR) by more than 15% at 10 years, from 28% without radiotherapy to 13 % with radiotherapy. Half of the recurrences …

EGFR
progesterone
chromogenic in situ hybridization
epidermal growth factor
treated by
  • 15 views
  • 25 Jan, 2021
  • 13 locations
Neoadjuvant Chemotherapy Followed by Radiotherapy Alone in Patients With Breast Cancer

After neoadjuvant chemotherapy, patients normally receive either conservative breast surgery or mastectomy followed by radiation therapy. Some patients achieve a complete response after neoadjuvant chemotherapy. Considering that radiation therapy is an effective treatment for subclinical microscopic disease, the question arises whether breast surgery before radiation therapy can be avoided in …

invasive breast cancer
erbb2
trastuzumab
HER2
mastectomy
  • 3 views
  • 21 Jan, 2021
  • 1 location
Comparison Between IORT and Postoperative Radiotherapy in Breast Conserving Surgery

To compare the satisfaction with conserved breast, acute and chronic postoperative complications and tumor control between intraoperative radiotherapy(IORT) and traditional postoperative radiotherapy following breast-conserving surgery (BCS).

  • 0 views
  • 21 Mar, 2021
  • 1 location
Evaluation of Mepitel Film in Preventing Epidermitis in Patients Receiving Radiation Therapy for Breast Cancer

The purpose of this research is to evaluate the use of Mepitel Film in preventing radiation epidermitis in patients receiving radiation treatment for breast cancer. Mepitel Film is a thin, flexible, waterproof, and breathable film made of a soft silicone layer and polyurethane film. Mepitel film is not made with …

burns
cancer
breast tumor
breast cancer
  • 0 views
  • 18 Mar, 2021
  • 6 locations
Trial Evaluating the Benefit of a Fitness Tracker Based Workout During Adjuvant Radiotherapy of Breast Cancer

This randomized three-arm trial will test the benefit in terms of cancer related fatigue of an activity tracker based exercise training during adjuvant radiotherapy in breast cancer patients.

cancer treatment
immunostimulant
breast-conserving surgery
  • 0 views
  • 25 Jan, 2021
  • 1 location
Pre- or Postoperative Accelerated Radiotherapy

20 non-metastasized breast cancer patients receiving neoadjuvant chemotherapy will be randomized between preop or postop RT. Patients with clinically suspicious axillary lymph nodes will receive a fine needle biopsy. Patients receiving postop RT will receive neoadjuvant CT followed by surgery (21-28 days after CT) and adjuvant RT starting 28-35 days …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Combined Optical and Infrared Imaging for Early Prediction of Erythema During Breast and Chestwall Radiotherapy

The aim of this study is to develop a computer model, based on photographs and heat images of patients' skin, to provide early prediction of painful reddening of the skin during radiotherapy treatment.

  • 0 views
  • 12 Mar, 2021
  • 1 location
Study of Stereotactic Radiotherapy for Breast Cancer

This is a Phase II trial of preoperative stereotactic radiation to the breast for low risk breast cancer.

carcinoma
sentinel node
erbb2
breast-conserving surgery
sentinel lymph node biopsy
  • 6 views
  • 28 Jan, 2021
  • 2 locations
A Study to Evaluate the Safety and Clinical Outcome of Using FR-Mask in Breast Cancer Patients With Radiation-irritated Skin After Radiotherapy

The breast radiotherapy after breast-conserving surgery reduces the risk of recurrence and death and is widely used for standard treatment for breast cancer. However, radiation dermatitis is a major adverse event of breast radiotherapy. Radiation-irritated skin is a treatment-induced symptom caused by radiation dose-limiting toxicity. It damages skin structure and …

lumpectomy
breast adenocarcinoma
breast-conserving surgery
  • 0 views
  • 23 Jan, 2021
  • 1 location
Demonstration of a Novel Approach Using Surface-Image Guidance to Improve Delivery of Breast Radiotherapy

The first goal of this project is to validate the superiority of semi-permanent marks used in conjunction with specialized light-based surface imaging (SIGRT) in an effort to phase out the use of permanent tattoos for the investigator's patients. The secondary goal of this project is to validate the superiority of …

carcinoma
ductal carcinoma in situ
invasive breast cancer
immunostimulant
ductal carcinoma
  • 66 views
  • 26 Jan, 2021
  • 1 location