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Found 15 clinical trials
Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients

The researchers plan: - To undertake clinical studies of radiotherapy with or without the administration of the chemotherapeutic agent cisplatin, known to be a radiosensitizer

chemotherapeutic agent
cervical carcinoma
cancer
radiosensitizer
  • 197 views
  • 07 Nov, 2020
  • 3 locations
A Safety and Efficacy of CCRT With Paclitaxel as Adjuvant Therapy to Post-Operative Advanced Endometrial Cancer Patients

The purpose of this study is to determine whether post-operative concurrent chemoradiation with paclitaxel is effective and safe in the treatment of high risk postoperative endometrial cancer patients.

hysterectomy
lymphadenectomy
adjuvant therapy
cancer
paclitaxel
  • 22 views
  • 07 Nov, 2020
  • 1 location
Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)

The purpose of this study is to determine the maximum tolerated dose of the chemotherapy drugs nab-paclitaxel and gemcitabine when combined with hypofractionated ablative proton therapy for the treatment of locally advanced pancreatic cancer. You will receive proton therapy once a day (Monday - Friday) for 3 weeks. Participants will …

  • 3 views
  • 25 Jan, 2021
  • 3 locations
Tri-weekly Cisplatin Based Chemoradiation in Locally Advanced Cervical Cancer

Current standard treatment for locally advanced cervical cancer is cisplatin-based concurrent chemoradiation (CRT). Although recently reported meta-analysis studies also demonstrated improved local control rates and survival with cisplatin-based chemotherapy concurrent to radiation therapy (RT), the optimal cisplatin dose and dosing schedule are still undetermined. In light of the results of …

adenosquamous carcinoma
brachytherapy
squamous cell carcinoma
cancer
concurrent chemoradiation
  • 133 views
  • 22 Jan, 2021
  • 6 locations
Sulfasalazine and Stereotactic Radiosurgery for Recurrent Glioblastoma

radiosensitizer.

temozolomide
karnofsky performance status
platelet count
gilbert's syndrome
recurrent glioblastoma
  • 3 views
  • 23 Jan, 2021
  • 1 location
Proton Therapy for Esophageal Cancer

advanced esophageal cancer and is also a potent radiosensitizer. Second, the substitution of carboplatin for cisplatin has resulted in reduced toxicity of various combination regimens similar to that used

esophageal cancer
esophagus cancer
endoscopy
endoscopic ultrasound
carboplatin
  • 77 views
  • 26 Feb, 2021
  • 1 location
Assessment of Gemcitabine as Chemoradiotherapy in Patients With Locally Advanced Carcinoma of Cervix and Renal Disease

patients. Venook et al. used gemcitabine as a radiosensitizer in patients with cancer and renal dysfunction. Our group, has observed encouraging results using gemcitabine as an alternative to cisplatin in

adenosquamous carcinoma
squamous cell carcinoma
gemcitabine
carcinoma
adenocarcinoma
  • 31 views
  • 24 Jan, 2021
  • 1 location
IA Carboplatin + Radiotherapy in Relapsing GBM

radiosensitizer such as carboplatin. Study design: In this phase I/II trial, patients will be treated at recurrence; a surgery will be performed for cytoreduction and to obtain tumor sample, followed with

temozolomide
renal function test
neutrophil count
measurable disease
MRI
  • 23 views
  • 22 Jan, 2021
Docetaxel-based Chemoradiotherapy Plus Periradiation Chemotherapy Compared With INT 0116 Adjuvant Arm in Gastric Cancer

Although the intergroup 0116 trial was the first to demonstrate that adjuvant chemoradiotherapy offers a significant survival benefit in completely resected gastric cancer,it is more toxic and less effective. It is reasonable to optimize this regimen.

fluorouracil
docetaxel
leucovorin
cancer chemotherapy
adenocarcinoma
  • 3 views
  • 25 Jan, 2021
  • 1 location
Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

The standard treatment for patients with Non-Small Cell Lung Cancer (NSCLC) and clinically negative lymph nodes remains surgery per current guidelines. Five year survival for patients with stage I non-small cell lung cancer is generally greater than 50% after surgery. Many of these patients have heart and lung issues or …

carboplatin
paclitaxel
lung carcinoma
cancer chemotherapy
carboplatin/paclitaxel
  • 18 views
  • 22 Jan, 2021
  • 1 location