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Found 9 clinical trials
Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer

The goal of this study is to evaluate combined radioactive iodine (RAI, 131-I) and external beam radiotherapy (XRT) to optimize the radiation dose delivered to treat well differentiated thyroid cancers (DTC) with iodine-avid metastases. The investigators hypothesize that precise dosimetric planning will permit this combined RAI-XRT radiotherapeutic approach to be …

  • 0 views
  • 09 Jun, 2022
  • 1 location
Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease (HEAD)

The purpose of this study is to compare/harmonize cross-sectional and longitudinal tau tangle measurements obtained with the tau PET radiopharmaceuticals Flortaucipir and MK-6240 to elucidate

mild cognitive impairment
dementia
senile plaques
cognitive impairment
alzheimer's disease
  • 0 views
  • 07 Oct, 2022
  • 1 location
Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma (CLOVER-2)

The study evaluates CLR 131 in children, adolescents, and young adults with relapsed or refractory malignant solid tumors and lymphoma and recurrent or refractory malignant brain tumors for which there are no standard treatment options with curative potential.

positron emission tomography
iobenguane
cancer
karnofsky performance status
sarcoma
  • 170 views
  • 12 Feb, 2022
  • 7 locations
68Ga-P16-093 and 68Ga-PSMA-11 PET/CT Imaging in the Same Group of Primary Prostate Cancer Patients

Prostate-specific membrane antigen (PSMA)-targeted PET imaging with 68Ga-labeled compounds is able to provide superior sensitivity and specificity to detect primary prostate tumor and its metastases, like the most widely studied 68Ga-PSMA-11. This pilot study was evaluate the diagnostic performance of 68Ga-P16-093, a novel radiopharmaceutical targeting PSMA, which was compared with …

  • 0 views
  • 07 Jul, 2022
  • 1 location
A Study of 68Ga-GRP PET/CT for Imaging in Low and Intermediate Risk Prostate Cancer

Patients with primary low and intermediate risk prostate cancer (PCa) for whom radical prostatectomy are indicated, will be invited to participate to the present study. The aim of this study is to investigate the clinical value of 68Ga-GRP positron emission tomography / computed tomography (PET/CT) compared to 68Ga-PSMA PET/CT in …

  • 0 views
  • 25 Oct, 2021
  • 1 location
Proof-of-concept Study of New Imaging Diagnostic in Patients With Suspected Alzheimer's Disease

This study is a Phase 1, first-in-human, multi-center study to establish safety of ADx-001 in healthy volunteers, and safety and proof of concept in patients with confirmed amyloid plaques in the brain (confirmed by amyloid positron emission tomography (PET)). ADx-001 is a novel, intravenously delivered, Gd- containing molecularly targeted liposomal …

positron emission tomography
amyloid
senile plaques
Accepts healthy volunteers
alzheimer's disease
  • 0 views
  • 04 Oct, 2022
  • 1 location
Ontario Provincial Registry Project for Cardiac Viability Assessment Using FDG PET (CADRE)

Positron Emission Tomography (PET) is a non-invasive, unique nuclear imaging technique that allows the evaluation of blood flow in the heart and provides information about the cell activity of specific organs such as the heart and brain. It also provides useful information for the management of patients with poor pumping …

positron emission tomography
heart failure
cancer
medical therapy
arterial disease
  • 88 views
  • 28 Oct, 2022
  • 4 locations
Whole Body Dynamic 68Ga-DOTATOC PET/CT in Neuroendocrine Tumors (GAPET-NET)

than PET technology and remains of limited interest for signal quantification. However, the ability to locate and quantitatively measure the absorption of radiopharmaceuticals in the target

positron emission tomography
cancer
18f-fdg
somatostatin
tetraxetan
  • 0 views
  • 05 Feb, 2022
  • 1 location
The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy

The study focuses on the development of a new personalized approach to diagnostics and surgical treatment of patients with ischemic cardiomyopathy. The algorithm for selection of patients for certain type of cardiac surgery will be developed. The models for prediction of the risks and outcomes of cardiac surgery will be …

coronary artery bypass graft
ejection fraction
stenosis
coronary bypass
infarct
  • 0 views
  • 15 Oct, 2021
  • 1 location