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Found 21 clinical trials
Pembrolizumab Plus Y90 Radioembolization in HCC Subjects

This is an open-label multi-center trial designed to evaluate the efficacy as well as the safety of combining pembrolizumab with Yttrium-90 (Y90) radioembolization in subjects with poor

ascites
radioembolization
prothrombin
systemic therapy
alpha fetoprotein
  • 104 views
  • 27 Jan, 2021
  • 3 locations
Yttrium-90 Radioembolization for Cirrhosis-Associated Thrombocytopenia

Evaluate the safety and efficacy of Yttrium-90 (90Y) radioembolization for the management of thrombocytopenia.

hepatic venous pressure gradient
carcinoma
varices
hepatocellular carcinoma
electrolytes
  • 4 views
  • 13 Mar, 2021
  • 1 location
HEPAR Primary: Holmium-166-radioembolization in Hepatocellular Carcinoma Patients

Patients with hepatocellular carcinoma often die from intrahepatic disease since current treatment options are generally limited. Local treatment using holmium radioembolization could offer an

radioembolization
tubal ligation
  • 4 views
  • 21 Jan, 2021
  • 2 locations
Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

This clinical trial will be conducted as a single-center, open-label, Phase I/2 trial to evaluate the feasibility and safety of Yttrium-90 radioembolization (Y90-RE) in combination with a fixed

liver metastasis
bevacizumab
EGFR
vascular endothelial growth factor
vegf
  • 0 views
  • 19 Jun, 2021
  • 1 location
90Y Transarterial Radioembolization (TARE) Plus Gemcitabine and Cisplatin in Unresectable Intrahepatic Cholangiocarcinoma

The purpose of this study is to determine the safety and maximum tolerated dose (MTD) of 90 Y TARE (Y90) in combination with gemcitabine and cisplatin in patients with unresectable intrahepatic cholangiocarcinoma (ICC).

cisplatin/gemcitabine
gemcitabine
unresectable intrahepatic cholangiocarcinoma
hepatectomy
cholangiocarcinoma
  • 5 views
  • 25 Jan, 2021
  • 1 location
Radioembolization for HCC Patients With Personalized Yttrium-90 Dosimetry for Curative Intent (RAPY90D)

This trial aims to improve hepatocellular carcinoma (HCC) tumor responses in patients undergoing Y90 radioembolization by using personalized dosimetry as part of treatment planning. Using

liver cancer
computed tomography
cancer
tumor cells
  • 0 views
  • 25 Jan, 2021
  • 1 location
Radioembolization of Primary and Secondary Liver Malignancies and The Effect On The Immune System

The goal of this study is to understand the immunologic effects radioembolization has on the immune system. This will be done by evaluating the changes on biopsy, peripheral blood monocytes, and

cytokines
cancer
carcinoma
radioembolization
hepatocellular carcinoma
  • 0 views
  • 26 Jan, 2021
  • 1 location
Perflutren Protein-Type A Microspheres and Contrast-Enhanced Ultrasound in Improving Response to Radioembolization Therapy in Patients With Liver Cancer

This phase II trial studies how well perflutren protein-type A microspheres and contrast-enhanced ultrasound work in improving response to radioembolization therapy in patients with liver cancer

cancer
carcinoma
radioembolization
liver cancer
hepatocellular carcinoma
  • 13 views
  • 09 Mar, 2021
  • 1 location
Y90 Radiation Segmentectomy vs SBRT for HCC

transarterial Y90 radioembolization (radiation segmentectomy) versus stereotactic body radiation therapy (SBRT) for solitary early stage ( 3cm) hepatocellular carcinoma (HCC).

serum bilirubin
  • 0 views
  • 25 Jan, 2021
Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow Surrounding HAE

to radioembolization and/or help demonstrate radiation toxicity to the surrounding liver.

anesthesia
radioembolization
hepatocellular carcinoma
measurable disease
tumor burden
  • 0 views
  • 22 Jul, 2021
  • 1 location