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Found 69 clinical trials
Eplerenone as a Supplement to Epidural Steroid Injections

Low back pain is a leading cause of disability and health care costs in the United States, and treatments are ineffective for many patients. Epidural steroid injections are a common treatment, but their efficacy has been questioned and for many patients they do not provide complete relief. The investigators hypothesize, …

radiculopathy
intervertebral disc degeneration
low back pain
back pain
  • 44 views
  • 04 Jun, 2022
  • 2 locations
Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With Cirrhosis

: radiculopathy, muscles, and headaches. [3,4]

liver disease
muscle spasms
electrolytes
calcium
cirrhosis
  • 2 views
  • 23 Jan, 2021
  • 1 location
Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease

The objective of this study is to perform a prospective, randomized, controlled clinical trial to compare radiographic fusion rates and patient reported outcomes, including pain and function preoperatively and postoperatively, using Depuy ViviGen® Cellular Bone Matrix mixed with cortical/cancellous allograft in conjunction with an approved Depuy Synthes pedicle screw system …

spinal stenosis
disc disease
bone graft
Accepts healthy volunteers
autograft
  • 13 views
  • 31 Dec, 2021
  • 1 location
An Investigation of the Metal Concentration in Patients Implanted With the PRESTIGE LP™ Cervical Disc at Two Contiguous Levels in the Cervical Spine

This clinical study will assess the metal concentrations present in the blood serum of patients who receive surgical treatment with the PRESTIGE LP™ Cervical Disc at two contiguous cervical levels from C3-C7. The information obtained from this clinical investigation will be used to support the post market surveillance for a …

spinal cord
spinal cord compression
myelopathy
disc disease
x-rays
  • 113 views
  • 11 Aug, 2022
  • 3 locations
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery (RCT-ESPB)

Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia. The erector spinae plane block (ESPB) is a promising locoregional anesthetic technique for this type of surgery. The literature is not yet conclusive about the effectiveness of this technique on reducing …

  • 6 views
  • 29 Jun, 2022
  • 1 location
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical patients. This study will serve …

  • 0 views
  • 12 May, 2022
  • 1 location
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and …

spinal cord
brain stimulation
stroke
limb pain
complex regional pain syndrome
  • 388 views
  • 15 Feb, 2022
  • 1 location
Effectiveness of a Training Protocol With the Cervical Device in Subjects With Deep Cervical Muscle Strength Deficit.

The purpose of this study is to evaluate the clinical results produced by a training protocol with the new device for cervical treatment (CDAT) and the conventional training protocol (CT) versus a control group (C) in subjects with cervical deep muscle strength deficit and mild neck disability.

  • 0 views
  • 21 Jul, 2022
  • 1 location
Effects of Mills Manipulation and Nirschel Exercises in Patients With Lateral Epicondylitis

To find effects of mills manipulation versus NIRSCHL EXERCISES on pain ,strength and function in patients with lateral epicondylitis.

Accepts healthy volunteers
tenderness
epicondylitis
  • 0 views
  • 02 Jul, 2022
  • 1 location
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy (Intra-Op)

The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.

conservative management
discectomy
radiculopathy
dexamethasone
  • 47 views
  • 19 Feb, 2022
  • 1 location