Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 59 clinical trials
Association of Platelet Parameters With Bleeding Severity in Children With ITP

Patients with severe immune thrombocytopenia (ITP) present with similarly low platelet counts but varying bleeding symptoms, making it difficult to predict the disease course and to decide on an appropriate treatment plan. In a single-center study, platelet parameters including the immature platelet fraction, the absolute immature platelet count , and …

autoimmune thrombocytopenia
platelet count
thrombocytopenia
  • 12 views
  • 15 Apr, 2021
  • 4 locations
Biological Bank for the Patients Followed in a Constitutive Reference Center for Autoimmune Cytopenia

The Internal Medicine Department of Haut-Lvque Hospital (Pr E LAZARO, Pr JL PELLEGRIN, Pr JF VIALLARD) was accredited in 2017 by the Ministry of Health as a Constitutive Reference Center for Autoimmune Cytopenia. The investigators wish to launch new research projects in autoimmune cytopenia and propose a translational and fundamental …

cytopenia
  • 3 views
  • 26 Jan, 2021
  • 1 location
Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy

Evaluate patient characteristics, treatment patterns, clinical outcomes and safety of fostamatinib as second-line therapy in real-world clinical practice, for the treatment of ITP in adult patients who have an insufficient response to prior therapy (steroids immunoglobulins).

immune globulin
fostamatinib
immunoglobulins
thrombocytopenia
  • 0 views
  • 28 Jul, 2021
  • 8 locations
Severe Immune Cytopenia Registry Www.Sic-reg.Org

Prospective registry study for children and young adults with severe immune cytopenias (persisting/chronic immune thrombocytopenia, autoimmune hemolytic anemia, and Evans syndrome) to improve the management, facilitate the differential diagnostic work-up, and document the clinical course under various treatments. Time points: at inclusion, after 6 months, after 12 months, then yearly …

cytopenia
autoimmune thrombocytopenia
thrombocytopenia
autoimmune hemolytic anemia
evans syndrome
  • 5 views
  • 02 Apr, 2021
  • 1 location
Long-term Sequelae of Childhood Meningitis and Meningococcal Purpura Fulminans

While the initial evolution of meningococcal meningitis (MM) is well described, there are few data on the long-term evolution, beyond 1 year. The objective of this research is to evaluate the sequelae of MM beyond 1 year in patients with a history of MM followed in Paris area, France. Most …

  • 0 views
  • 12 Aug, 2021
  • 1 location
Retrospective Analysis of the Efficiency of Caplacizumab in the Treatment of aTTP

The objective of this national, prospective, multi-centre observational study is to describe the prescription rational and practice in Germany, confirm the efficacy of caplacizumab in a real-world setting, and identify predicting factors in iTTP-patients with regard to persistent autoimmune activity, therapy guidance and risk of complications. The rational is to …

  • 0 views
  • 10 Aug, 2021
  • 1 location
Biorepository and Registry for Plasma Exchange Patients

Patients who have immune mediated diseases commonly undergo plasma exchange (PLEX) procedures to remove pathological substances, typically believed to be antibodies. At our facility about 400 of these procedures are performed annually on 40-60 different patients. These procedures are considered within the standard of care for these patients and are …

immune globulin
plasma exchange
cell counts
  • 0 views
  • 22 Aug, 2021
  • 1 location
Levels of Von Willebrand Factor Multimers and VWF-Cleaving Protease (ADAMTS-13) in Preterm and Neonate

ULVWF will bind to platlets resulting in systemic thrombotic microangiophaties (TMA) such as thrombotic thrombocytopenic purpura(TTP)(5,6). ADAMTS-13 belongs to the ADAMTS family of

  • 0 views
  • 07 Nov, 2020
  • 1 location
Vasculitis Pregnancy Registry

The purpose of this study is to learn about the experience of women with vasculitis who become pregnant. In particular, the study will consist of several online surveys to assess each woman's vasculitis severity and pregnancy-related experiences, and pregnancy outcomes.

purpura
wegener's granulomatosis
eosinophilic granulomatosis
microscopic polyangiitis
central nervous system vasculitis
  • 120 views
  • 27 Apr, 2021
  • 1 location