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Found 61 clinical trials
The Combination of Tacrolimus and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia

Randomized, open-label, multicenter study to compare the efficacy and safety of Combination of High-dose Dexamethasone and Tacrolimus versus High-dose Dexamethasone for the first-line treatment of adults with primary immune thrombocytopenia (ITP).

  • 0 views
  • 18 Feb, 2021
  • 1 location
A Multicenter Randomized Open-label Study of Diammonium Glycyrrhizinate Enteric-coated Capsule Plus DXM Versus DXM in Treatment of ITP

The project was undertaking by Qilu Hospital of Shandong University in China. In order to report the efficacy and safety of diammonium glycyrrhizinate enteric-coated capsule plus high-dose dexamethasone for the treatment of adults with newly-diagnosed primary immune thrombocytopenia (ITP).

platelet count
thrombocytopenia
dexamethasone
  • 0 views
  • 03 Sep, 2021
  • 2 locations
Dietary Phytoestrogens as Risk Factors for Systemic Lupus Erythematosus

The study aims at determining if dietary phytoestrogens can be risk factors for Systemic Lupus Erythematosus (SLE). Dietary enquiry and phytoestrogens measurements will be performed in blood and urine of patients with SLE in an active phase of the disease, in patient with other autoimmune diseases and in healthy volunteers. …

autoimmune disease
lupus
  • 41 views
  • 26 Jan, 2021
  • 1 location
Autoreactivity Threshold Analysis in Lupus and Immune Thrombocytopenia (Checkpoints ITP and SLE)

The aim of this proposal is to test if anti-BAFF antibody can restore a normal threshold of tolerance in patients in two auto-immune diseases along the RITUX-PLUS study in immune thrombocytopenia, and along the Believe study in SLE. This work would help to conclude whether or not the 'double hit' …

immune globulin
thrombocytopenia
baff
immune tolerance
lupus
  • 0 views
  • 30 May, 2021
  • 2 locations
Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis

Immune thrombocytopenia (ITP) is an autoimmune disease but, paradoxically, and unlike other autoimmune diseases, antiplatelet antibodies are not used either for the diagnosis of the disease or for its prognosis. ITP is a diagnosis of exclusion retained after elimination of other pathologies leading to a thrombocytopenia. No major study has …

thrombocytopenia
autoimmune disease
platelet aggregation
acute leukemia
monoclonal antibodies
  • 0 views
  • 02 Jun, 2021
  • 1 location
Eltrombopag Combined With Low-dose Rituximab in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, nonrandomized, multicenter clinical trial aims at comparing the efficacy and safety of combined use of eltrombopag with low-dose rituximab vs. the best available therapyBATin adult immune thrombocytopenia with autoantibodies fail (due to intolerance or resistance) to first-line treatment.

glucocorticoids
rituximab
immune tolerance
immune globulin
platelet count
  • 0 views
  • 14 Jun, 2021
  • 1 location
Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, single-center, one-arm clinical trial aims at evaluating the efficacy and safety of avatrombopag in Chinese adult Immune Thrombocytopenia (ITP) patients with autoantibodies fail (due to intolerance or resistance) to eltrombopag or herombopag treatment.

thrombocytopenia
arthritis
glucocorticoids
thrombopoietin receptor agonists
eltrombopag
  • 0 views
  • 12 Aug, 2021
  • 1 location
Safety and Efficacy of Fecal Microbiota Transplantation

, dysbiotic bowel syndrome, MRSA enteritis, Pseudomembranous enteritis, idiopathic thrombocytopenic purpura (ITP), and atopy. Despite FMT appears to be relatively safe and efficacious in treating a

hepatic encephalopathy
carbapenem
MRSA
ulceration
graft-versus-host disease
  • 313 views
  • 24 Jan, 2021
  • 1 location
to Evaluate the Efficacy and Safety of Eltrombopag for Thrombocytopenia With Chronic HBV Infection

Primary Objective: To evaluate the efficacy of 6-week Eltrombopag to treat thrombocytopenia associated with chronic hepatitis B virus infection. Secondary Objective: To evaluate the efficacy and safety of 6-week and 22-week Eltrombopag to treat thrombocytopenia associated with chronic hepatitis B virus infection.

  • 0 views
  • 10 Jul, 2021
  • 1 location
Rituximab in Patients With Relapsed or Refractory TTP-HUS

The general objective of this study is to assess the efficacy and safety of Rituximab in the management of patients with refractory or relapsed thrombotic thrombocytopenic purpura

  • 54 views
  • 07 Nov, 2020
  • 8 locations