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Found 55 clinical trials
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

anemia studies
myelodysplastic syndrome (mds)
myelodysplastic syndromes
aplastic anemia
  • 22 Dec, 2020
  • 1 location
A Study of BAX 930 in Children Teenagers and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Thrombotic thrombocytopenic purpura (or TTP for short) is a condition where blood clots form in small blood vessels. This means the cells that help the blood to clot (platelets) are lower in the

  • 16 May, 2021
  • 37 locations
A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura

The main aim of the study is to check for side effects of TAK-755. Participants will either receive TAK-755 every week or every other week to prevent bleeds (prophylactic arm) or they will receive TAK-755 to treat an acute bleed (on-demand arm). Participants in the prophylactic arm will receive treatment …

  • 16 May, 2021
  • 22 locations
Study of Doxil in the Treatment of Patients With Refractory Idiopathic Thrombocytopenic Purpura

This study is designed to evaluate the efficacy and safety of single agent Doxil in the treatment of patients with refractory ITP (Idiopathic Thrombocytopenic Purpura).

immune globulin
  • 07 Nov, 2020
  • 1 location
Clinical Study on Strategy for Refractory Henoch-Sch nlein Purpura

IgA vasculitis is relatively common in children,especially in Asian countries. Abdominal manifestation could be severe, including bleeding, pancreatitis,appendicitis and intestinal intussusception. Delayed diagnosis could be fatal and cause severe complications.Nowadays no guidelines for those with severe abdominal manifestations in China.However, the most used treatment is steroid. For those severe forms …

  • 26 Jan, 2021
  • 3 locations
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-sch nlein Purpura

The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with Henoch-schnlein purpura.

  • 24 Jan, 2021
  • 1 location
A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP

To select a dose and to make a decision for Phase 3 study

  • 17 Feb, 2021
  • 1 location
A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast Cancer

The aim of this study was to evaluate the progression time and efficacy of brain tumors in patients with brain metastases from HER2-positive breast cancer treated with Pyrrolidine and Capecitabine combined with brain radiotherapy.

  • 03 Mar, 2021
  • 1 location
Eltrombopag+hATG+CsA vs. hATG+CsA in Children With Severe AA

The analysis of our own clinical data suggests that majority of the hematologic responses observed after the course of h-ATG/CsA is partial, and about 10% tend to have cyclosporine dependence. The aim of the current study is to improve the rate and the quality of hematologic response as well as …

  • 21 Mar, 2021
  • 1 location
Safety and Tolerability of M254 in Healthy Volunteers and Immune Thrombocytopenic Purpura (ITP) Patients

and immune thrombocytopenic purpura (ITP) patients. The pharmacodynamics of the drug will be measured as platelet response in patients with ITP.

immune globulin
  • 02 Apr, 2021
  • 30 locations