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Found 6 clinical trials
Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome

Open label, phase II study non randomized single group assignment of 20 evaluable patients 13 years and older, over 37,5 kg body-weight, with sensorineural hearing loss of at least 20 dB at 8 kHz in high frequency average (HFA), and with documented genetic mutations in the WFS1 gene and with …

  • 0 views
  • 18 Dec, 2021
  • 1 location
Middle-ear Reflex Testing Using Wideband Acoustic Immittance

This project will assess the middle-ear muscle reflex using wideband acoustic immittance which is a valuable method for evaluating infants, children, and adults. The developments will facilitate clinical applications that include hearing screening and diagnostic evaluation of persons of all ages with normal hearing and with hearing loss.

  • 0 views
  • 14 Aug, 2021
  • 1 location
Ph.D.-Project: Eustachian Tube Dysfunction: Causes Diagnosis Treatment and Prognosis

Background The Eustachian Tube (ET) is a mucosa-lined connection between the nasopharynx and the middle ear cavity. It is believed to have three functions: 1) ventilation of and pressure equalization in the middle ear cavity, 2) mucus drainage from the middle ear, and 3) protection against sound and infection from …

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  • 01 Oct, 2021
  • 1 location
A Study in Radiotherapy-related Nervous System Complications

Purpose: This observational study aims to evaluate the clinical manifestations, therapeutic effects, progress and prognosis in radiotherapy-related nervous system complications. OUTLINE: This is an observational clinical trial. Patients are enrolled and administrated with optimized clinical treatment. Blood, urine, stool, cerebrospinal fluid (CSF), imaging and other examinations, and scale assessments are …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Study of Diagnostic Biomarkers of Acute Acoustic Trauma

-induced hearing impairment. They are multiple and pure tone audiometry, the only reference examination, does not allow to differentiate them. Moreover, in the aftermath of acute acoustic trauma, pure

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  • 29 Apr, 2021
  • 1 location
Genotype-phenotype Correlation Study of Presymptomatic and Symptomatic DFNA9 Patients

DFNA9 (Deafness Autosomal Dominant 9) is an autosomal dominant hereditary hearing loss which is associated with vestibular deterioration. The most recent genotype-phenotype correlation studies have been conducted more than 15 years ago. Meanwhile, emerging and valuable vestibular tests have been added to the vestibular test battery. These tests were not …

hereditary hearing loss
dfna9
deafness
  • 0 views
  • 15 Feb, 2022
  • 1 location