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Found 131 clinical trials
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Actigraphy Improvement With Voxelotor (ActIVe) Study

This is a study to evaluate the effect of voxelotor on daily physical activity and sleep quality, as measured by a wrist-worn device in participants with sickle cell disease (SCD) and chronic moderate anemia.

glutamine
sickle hemoglobin
thalassemia
hydroxyurea
thal
  • 0 views
  • 10 Nov, 2021
  • 11 locations
None
Efficacy and Safety of Dexmedetomidine in the Analgesic Prophylaxis in Patients Undergoing Cardiovascular Surgery

Acute pain is one of the complications after cardiothoracic surgeries . It can delay patientsrecovery and may increase patientsmorbity and mortality. This study intends to evaluate Dexmedetomidine, a highly selective - 2 receptor agonist, that is currently applied safely and efficiently in intraoperative cardiac surgery. It has analgesic, sedative, anxiolytic …

acute pain
cardiovascular surgery
sedative
anesthesia
cardiopulmonary bypass
  • 0 views
  • 28 Oct, 2021
  • 2 locations
None
High-Flow Nasal Oxygen Therapy for Exacerbation of Chronic Pulmonary Obstructive Disease.

High-Flow Nasal Oxygen (HFNO) therapy has never been tested against Noninvasive ventilation, the reference standard therapy for acute exacerbation of chronic obstructive pulmonary disease (COPD), in randomized clinical trials. The aim of the present study is to compare the effects of HFNO therapy on arterial blood gas variables over the …

carbon dioxide
acute exacerbation of chronic obstructive pulmonary disease
non-invasive ventilation
arterial blood gases
  • 33 views
  • 02 Nov, 2021
  • 3 locations
None
CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial

The purpose of this study is to determine if in preterm infants < 34 weeks' gestation at birth receiving respiratory support with continuous positive airway pressure (CPAP) or nasal cannula (NC), CPAP compared with NC will decrease the number of episodes with oxygen saturations less than 85% of 10 seconds …

  • 0 views
  • 01 Sep, 2021
  • 1 location
None
Perioperative Telemonitoring to Optimize Cancer Care and Outcomes

This study aims to see whether an at-home monitoring program that collects health, symptoms, and quality of life data in real-time can be included as part of the care of surgery patients in order to provide better recovery. Patient-generated health data (weight, temperature, oxygen level, heart rate, blood pressure, daily …

  • 0 views
  • 02 Dec, 2021
  • 1 location
None
Long-term Oxygen Therapy in Patients With Chronic Obstructive Pulmonary Disease Who Live at High Altitude

A clinical, prospective, randomized controlled trial to determine the effect of prescribing oxygen in a group of COPD (chronic pulmonary disease) patients with PaO2 (arterial oxygen tension) 50 and 55 mmHg who do not have erythrocytosis or pulmonary hypertension on echocardiogram (which are considered manifestations of chronic hypoxia)

bronchodilator
wheezing
long-term oxygen therapy
asthma
cough
  • 11 views
  • 15 Mar, 2021
  • 2 locations
None
A Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases

Background The COVID-19 outbreak has strained the health care system. New tools are needed for diagnostic testing and monitoring of people who have the virus. Researchers want to test a device they hope can screen, detect, and monitor symptoms linked to respiratory diseases like COVID-19. Objective To evaluate and validate …

Accepts healthy volunteers
fever
strain
sneezing
cough
  • 0 views
  • 08 Dec, 2021
  • 1 location
None
Prone Positioning on Admission for Hospitalized COVID-19 Pneumonia Protocol

A pilot study to investigate the effects of the prone positioning (PP) on hospital patients diagnosed with COVID-19 pneumonia. Investigators that early self-proning may prevent intubation and improve mortality in patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2). Up to 100 participants with a primary diagnosis of confirmed COVID-19 …

coronavirus infection
covid-19
respiratory failure
SARS
pneumonia
  • 73 views
  • 26 Jun, 2021
  • 3 locations
None
Comparing Fascia Iliaca Compartment Block and Pericapsular Nerve Group Block for Hip Fracture Pain Control

The aim of the study is to compare the analgesic effect of fascia iliaca compartment block (FIC) block and pericapsular nerve group (PENG) block in hip fracture pain control. The participants, caregivers, and assessors will be blinded to the type of block the participants receive. Patients aged 20 years or …

nerve block
analgesia
hip fracture
ultrasound guidance
anesthesia
  • 0 views
  • 08 Mar, 2021
  • 1 location
None
Sleep Health Program for Patients With Chronic Pain

This is a pilot, prospective, randomized controlled trial of a novel sleep health program versus no sleep intervention in chronic pain patients. The Sleep Health program will consist of weekly home-based videos and digital materials termed "Self-Management for Sleep Care", which will provide participants with information on how to improve …

cancer
cancer pain
apnea
sleep disturbances
chronic pain
  • 120 views
  • 25 Jan, 2021
  • 5 locations