Found 127 clinical trials
Eliminating Monitor Overuse Trial (EMO Trial)
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who
- 0 views
- 25 Mar, 2022
- 16 locations
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients
Multicenter double-blind placebo-controlled parallel-group randomized clinical trial of efficacy and safety of Raphamin in the treatment of coronavirus disease 2019 in outpatients.
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- 16 May, 2022
- 8 locations
VAPORHCS/OHSU J: MRI and Devices
This is a database study of clinically indicated MRIs on patients with permanent pacemakers and implantable cardioverter defibrillators.
- 0 views
- 02 Feb, 2022
- 2 locations
Trans-abdominal Fetal Pulse Oximetry; Tissue Light Scattering and Signal Integrity
The overall purpose of this study is to evaluate maternal-fetal tissue light scattering properties. The objectives of the study are: (i) integrate established mathematical principles of oxygen saturation to model with increasing accuracy the "body in a body" problem of fetus in mother; similar to existing pulse oximeters, the calculations …
- 1 views
- 13 May, 2022
- 1 location
Hyperbaric Oxygen for Long COVID-19 Pulmonary Sequela
measurements (low dose chest computer tomography (CT), Ventilation/perfusion with magnetic resonance imaging (VA/Q MRI), cardiopulmonary exercise testing with pulse oximetry (SpO2) and spirometry including
- 0 views
- 22 Nov, 2021
- 1 location
Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies
This is a Phase 1 dose-escalation study to evaluate the safety and tolerability of combination treatment of AZD5363 + Olaparib + Durvalumab and to determine the RP2D in patients with advanced or metastatic solid tumor malignancies. The purpose of this trial is to determine if combination treatment of drugs, Olaparib, …
- 0 views
- 22 Jan, 2021
- 1 location
Dexmedetomidine in Splanchnic Nerve Neurolysis
Malignancy related abdominal and pelvic pain can be debilitating and affects survival as well as quality of life. Pain from cancer and its treatments can result in anxiety, depression, fear, anger, helplessness, and hopelessness, and those with both pain and depression have an amplification of disability and poor quality of …
- 0 views
- 06 Apr, 2022
- 1 location
A Study of Agreement Between Oxygen Saturation Measured by Two Probes in Infants on the Neonatal Unit
On the neonatal unit in Derby, two types of probes are in routine use: Mindray 520 N and Mindray 521 N. Feedback from parents and staff show that there are concerns that the two probes given very different oxygen saturation readings and, often, do not agree with each other. This …
- 0 views
- 10 Oct, 2021
- 1 location
Negative Pressure Ventilation in Paediatric Patients During Weaning (NEGWEAN)
Negative pressure ventilation (NPV) represent a unique form of noninvasive ventilation using negative pressure by specialized cuirass, that evolve negative pressure on the front size of chest and partially abdomen and facilitate the spontaneous breathing. The benefit of NPV beside noninvasive application, is the supreme tolerance of the patient (compared …
- 0 views
- 26 Mar, 2022
- 1 location
Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study) (NAIFI01)
The investigators aim to assess the safety and efficacy of nebulized liposomal amphotericin B (ALN) as a complementary therapy to the usual systemic treatment in patients with invasive pulmonary aspergillosis and the utility of a non-routine test as a surrogate marker of efficacy. To this end, a 3-year phase I, …
- 38 views
- 27 Feb, 2022
- 1 location