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Found 209 clinical trials
A Double Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of PRA023 in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (ATHENA-SSc-ILD)

The purpose of this study is to assess the safety and efficacy of PRA023 in participants with SSc-ILD .

interstitial lung disease
progressive systemic sclerosis
methotrexate
carbon monoxide
azathioprine
  • 0 views
  • 11 Oct, 2022
  • 17 locations
An Open-label Trial of the Long-term Safety and Tolerability of Nintedanib Per os, on Top of Standard of Care, Over at Least 2 Years, in Children and Adolescents With Clinically Significant Fibrosing Interstitial Lung Disease (InPedILD®-ON)

This study is open to children and adolescents with interstitial lung disease (ILD) that causes lung fibrosis. This is a study for people who took part in a previous study (study 1199-0337

  • 0 views
  • 24 Oct, 2022
  • 27 locations
A Double Blind, Randomized, Placebo-controlled Trial Evaluating the Efficacy and Safety of BI 1015550 Over at Least 52 Weeks in Patients With Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs)

This study is open to adults with Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs). People who have a form of PF-ILD other than Idiopathic Pulmonary Fibrosis (IPF) can join the study

  • 0 views
  • 21 Oct, 2022
  • 1 location
GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis (GKT137831)

A placebo-controlled, multicenter, randomized trial to test GKT137831 in ambulatory patients with idiopathic pulmonary fibrosis. This drug is an inhibitor of nicotinamide adenine dinucleotide

pulmonary disease
forced vital capacity
idiopathic pulmonary fibrosis
  • 27 views
  • 02 May, 2022
  • 1 location
Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).

Idiopathic Pulmonary Fibrosis (IPF) is a progressive lung disease marked by reduced exercise capacity and activity-related breathlessness (commonly termed dyspnea). Our previous work has shown

interstitial lung disease
Accepts healthy volunteers
nitric oxide
idiopathic pulmonary fibrosis
dyspnea
  • 0 views
  • 06 May, 2022
  • 1 location
IPF mHealth Exercise

Patients with idiopathic pulmonary fibrosis (IPF) who are stable on antifibrotic therapy at least 3 months will be randomized to complete a 12-week home exercise intervention using an mHealth

nintedanib
diffusion capacity of the lung for carbon monoxide
carbon monoxide
idiopathic pulmonary fibrosis
carbon monoxide diffusing capacity
  • 0 views
  • 18 Oct, 2021
  • 1 location
FAPI PET for Lung Fibrosis (FAPI ILD)

This is a prospective exploratory biodistribution study in patients with interstitial lung disease (ILD). The purpose of this research study is to determine where and to which degree the FAPI tracer (68Ga-FAPI-46) accumulates in normal and fibrotic lung tissues of patients with interstitial lung disease. The study will include patients …

interstitial lung disease
ct scan
pulmonary fibrosis
lung biopsy
pneumonia
  • 0 views
  • 30 May, 2022
  • 1 location
Genentech Xenon MRI Idiopathic Pulmonary Fibrosis

changes over time in Idiopathic Pulmonary Fibrosis (IPF) patients receiving approved IPF treatments. Subjects will undergo an approximately hour long comprehensive MRI protocol, including

nintedanib
ct scan
pirfenidone
idiopathic pulmonary fibrosis
pulmonary function test
  • 4 views
  • 18 May, 2022
  • 1 location
Phase 1b Double-Blind, Placebo-Controlled, Ascending Dose Trial: ORIN1001 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

up to 28 days in adult subjects with idiopathic pulmonary fibrosis (IPF) alone or in conjunction with local Standard of Care for IPF (pirfenidone or nintedanib). A maximum of 24 evaluable

nintedanib
idiopathic pulmonary fibrosis
pneumonia
lung biopsy
interstitial lung disease
  • 4 views
  • 11 Oct, 2022
  • 11 locations
Jaktinib Dihydrochloride Monohydrate in Idiopathic Pulmonary Fibrosis

Jaktinib Dihydrochloride Monohydrate for idiopathic pulmonary fibrosis

acetylcysteine
idiopathic pulmonary fibrosis
  • 35 views
  • 10 Dec, 2021
  • 1 location