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Found 209 clinical trials
Hyperpolarized Xenon-129 MR Imaging of the Lung

Over the past 10 years, electronic cigarettes (e-cigarettes, EC) have been commercialized as a "less harmful" alternative to traditional cigarettes.1,2 However, e-cigarettes are believed to cause pulmonary epithelial, endothelial and vascular dysfunction, and to cause murine phenotypes similar to those of human COPD. Recently, "spiked" vape juice has been linked …

  • 27 views
  • 26 Jan, 2021
  • 1 location
Sputum Microbiota and the Association With Clinical Parameters in Steady-state Acute Exacerbation and Convalescence of Bronchiectasis

Study 1 is a cross-sectional investigation. Patients with clinically stable bronchiectasis (symptoms, including cough frequency, sputum volume and purulence, within normal daily variations) will undergo baseline assessment consisting of history taking, routine sputum culture, 16srRNA pyrosequencing, measurement of sputum inflammatory markers, oxidative stress biomarkers and MMPs, and spirometry. Microbiota taxa …

sputum culture
cough
spirometry
grip
antibiotics
  • 29 views
  • 23 Jan, 2021
  • 1 location
The Influence of Telerehabilitation Focused on Respiratory Muscle Training

Pulmonary rehabilitation, which includes respiratory muscle training, is effective in improving the functional status of patients with various types of the respiratory system diseases, including bronchial asthma, interstitial lung diseases or lung transplant patients. However, availability of pulmonary rehabilitation is limited in the Czech Republic. Nowadays even more due to …

  • 0 views
  • 07 Oct, 2022
  • 1 location
Muscle Strength Exercise and Sleep Apnea

Background Obstructive sleep apnea is one of our common diseases and up to 80% of patients are estimated to be undiagnosed. Its main risk factors are overweight, age, male gender, menopause, small jaw, sedative medications / drugs and alcohol. The most important treatment for sleep apnea is continuous positive airway …

obstructive sleep apnea
dyspnea
continuous positive airway pressure
sedative
  • 10 views
  • 23 Apr, 2022
Zephyrus II: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Pamrevlumab in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis (IPF). There is a 48-week randomized treatment phase followed by an optional, open-label extension phase.

pamrevlumab
diffusion capacity of the lung for carbon monoxide
idiopathic pulmonary fibrosis
pirfenidone
nintedanib
  • 67 views
  • 18 Oct, 2022
  • 127 locations
  • 23 views
  • 24 Oct, 2022
  • 228 locations
A Double Blind, Randomized, Placebo-controlled Trial Evaluating the Efficacy and Safety of BI 1015550 Over at Least 52 Weeks in Patients With Idiopathic Pulmonary Fibrosis (IPF)

This study is open to adults with a lung disease called Idiopathic Pulmonary Fibrosis (IPF). People can join the study if they are 40 years or older. If they already take nintedanib or

diffusion capacity of the lung for carbon monoxide
idiopathic pulmonary fibrosis
pirfenidone
nintedanib
forced vital capacity
  • 0 views
  • 28 Oct, 2022
  • 5 locations
A Phase III Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis (STARSCAPE)

with idiopathic pulmonary fibrosis (IPF).

diffusion capacity of the lung for carbon monoxide
6-minute walk test
lung biopsy
prm-151
walk tests
  • 29 views
  • 24 Oct, 2022
  • 330 locations
  • 6 views
  • 23 Oct, 2022
  • 35 locations
Exhaled Breath Analysis Using eNose Technology as a Biomarker for Diagnosis and Disease Progression in Fibrotic ILD

The ILDnose study a multinational, multicenter, prospective, longitudinal study in outpatients with pulmonary fibrosis. The aim is to assess the accuracy of eNose technology as diagnostic tool

  • 0 views
  • 04 Oct, 2022
  • 4 locations